IRCT20200208046414N1 IRCT 2020-04-04 Ghoum University of Medical Sciences "Effect of propofol in severe intracerebral hemorrhage " ICH( intracerebral hemorrhage) Comparison of the efficacy of intravenous propofol infusion with conservative treatment in outcome of patients with severe intracerebral hemorrhage hospital based 2020-04-20 anticipated 112 Complete https://irct.ir/trial/45658 interventional Randomization: Not randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Blinding description: At all stages of the study, the researchers responsible for evaluating the outcome of the patients would be blind to the grouping performed. 3 Nontraumatic intracranial hemorrhage. Intervention 1: In addition to routine treatment and care, a 25-75 µg / kg / min intravenous infusion will be used within the first 24 hours. NIHSS, GCS and bleeding volume will be recorded on arrival and daily for up to 7 days. Also, mortality rate, duration of hospitalization, extent of hemorrhage and mRS, NIHSS, GCS in the group receiving propofol will be compared using appropriate statistical tests. Cardiac wall, measurement of oxygen saturation of peripheral blood by pulse oxy meters, standard neurological treatments and standard rehabilitation measures will be performed. Intervention 2: Control group: In patients of the intervention group routine supportive measures in patients with intracerebral hemorrhage hospitalized in the intensive care unit such as blood pressure measurement, ECG monitoring, measurement of peripheral blood oxygen saturation by pulse oximeter, standard neurological treatments and Standard rehabilitation procedures will be performed. All demographic and clinical information of patients will be recorded in questionnaires designed by researchers and the amount of mRS, NIHSS, GCS and bleeding volume will be recorded at the beginning of the day and up to 7 days. Also, mortality rate, duration of hospitalization, extent of hemorrhage expansion and rate of mRS, NIHSS, GCS in the control group will be compared using appropriate statistical tests. Standard neurological treatments and standard rehabilitation measures will be performed. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information