]>
IRCT20141123020052N3 IRCT 2020-08-06 Islamic Azad University Efficacy of combinig fractional 1550nm laser and topical Sina-ampholish in old world cutaneous leishnaniasis Evaluating the effect of combination of fractional 1550nm laser therapy plus Sina-ampholeish ointment on cutaneous leishmaniasis 2019-12-22 anticipated 65 Complete https://irct.ir/trial/45265 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 3 Skin lesions caused by cutaneous leishmaniasis. Intervention 1: Intervention group: Selected skin lesions are treated in 6 pass with fractional laser of 1550nm wave length with 40mj energy in each MTZ weekly for 6 weeks. Sina-Ampholish cream used twice daily during the treatment. Intervention 2: Control group: one lesion with average diameter of all skin lesions is selected as control and no treatment is given. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information
public Ahmadreza parhizkar
Level 3, Hafez street, next to Mellat Bank, Fasa, Fars province, Iran,
Fasa Iran (Islamic Republic of) 7461917949 +98 71 5335 5222 ahmadrparhizkar@yahoo.com Islamic azad university of kazerun scientific Ahmadreza parhizkar
Level 3, Hafez street, next to Mellat Bank, Fasa, Fars province, Iran,
Fasa Iran (Islamic Republic of) 7461917949 +98 71 5335 5222 ahmadrparhizkar@yahoo.com Islamic azad university of kazerun Iran (Islamic Republic of) Less than 1months of the disease duration Written informed consent. at least 2 skin lesions present 5 years 60 years Both Concurrent Koebner positive skin disorders patient who treating under immunodeficient drugs Skin phototype FitzPatrick V and VI patient below 5 years old lesions on the face lesions of more than 4 centimeter diameter patients who have underlying liver or kidney disease B55.1 Cutaneous leishmaniasis treatment laser Treatment - Devices Treatment - Devices Intervention group: Selected skin lesions are treated in 6 pass with fractional laser of 1550nm wave length with 40mj energy in each MTZ weekly for 6 weeks. Sina-Ampholish cream used twice daily during the treatment Control group: one lesion with average diameter of all skin lesions is selected as control and no treatment is given. Induration of the lesion. Timepoint: Before intervention and 1, 2, 3, 4, 5, 6 weeks after intervention and 4 weeks after the end of treatment. Method of measurement: The degree of stiffness in touch by the researcher. Ulcer diameter. Timepoint: Before intervention and 1, 2, 3, 4, 5, 6 weeks after intervention and 4 weeks after the end of treatment. Method of measurement: By the ruler. Lesion diameter. Timepoint: Before intervention and 1, 2, 3, 4, 5, 6 weeks after intervention and 4 weeks after the end of treatment. Method of measurement: By the ruler. Fasa University of Medical Sciences Dr. Ahmadreza Parhizkar Dr. Ahmadreza Parhizkar Approved 2019-10-01 Ethics committee of Islamic Azad University Kazerun branch Central office of Islamic Azad University., North Ghaani Ave., Shiraz Town, Kazerun Fars Iran (Islamic Republic of) Approved 2020-07-14 Ethics committee of Fasa University of Medical Sciences Fasa University of Medical Sciences, Ebn-Sina Square Fasa Fars Iran (Islamic Republic of)