IRCT20120112008712N4 IRCT 2020-03-03 Maragheh University of Medical Sciences Honey and butter in treatment of burning The Effect of Adding Combination of honey and butter to Silver Sulfadiazine on Healing Time and Infection Rate in Second-degree Burning: Randomized Controlled Clinical Trial 2020-03-10 anticipated 70 Complete https://irct.ir/trial/45144 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients will be randomly assigned to intervention and control groups based on permissive block design. First, a single-digit random number will be generated if the chosen number is 0 to 4 AB permutation will be used and if it is between 5 and 9 BA permutation will be used. This method will be employed to complete the sample size, Blinding description: All Patients, nurses, and doctors, as well as statistical analyzers, will be unaware of the treatment codes. 3 Burn of second degree. Intervention 1: In the intervention group: Before examining the wound, patients will be examined by a physician, based on a checklist. After washing and drying the burned tissue, kefir ointment and 10% extract of Malva sylvestris is applied to the wound area. Silver sulfadiazine 1% ointment is then applied and the wound will be dressed. In this study, wound healing would be evaluated on days 1, 3, 7 and 14 after-burn. Intervention 2: In the control group: Before examining the wound, patients are examined by a physician based on a standard checklist. Then the limb or the burned area is washed with normal saline and dried by sterile gas. Silver sulfadiazine 1% ointment would be applied with sterile gloves on the wound. In this study, wound healing would be evaluated on days 1, 3, 7 and 14 after-burn. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is It is not yet known if there will be a plan to make this available