IRCT20200113046121N1 IRCT 2020-02-18 Khoram-Abad University of Medical Sciences Effect of Balanced Salt Solution on Dry eye Effectiveness of Balanced Salt Solution on Dry eye in Hospitalized Comatose Patients in Intensive care units 2019-07-23 anticipated 40 Complete https://irct.ir/trial/45097 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: Random assignment to intervention and control groups: Coin toss will be used to allocate each eye to two treatments (simple random allocation), with one eye assigned to the case group and the other to the control group, Blinding description: Clinical care nurses will not be aware of the type of solution used (label A, B will be available on both solutions) The optometrist will be unaware of the type of care The data analyzer will also be unaware of the type of care. 3 dry eye. Intervention 1: Intervention group:1-Schimmer test and TBUT for Dry eye examination before intervention by an optometrist 2-Wash hands before eye care 3-Applying a Balanced Salt Solution every 6 hours (2 drops) will also be followed by sterile eye ointment and adhesive tape on the eye. Intervention 2: Control group: 1-Schimmer test and TBUT for Dry eye examination before intervention by an optometrist 2-Wash hands before eye care 3-Applying a artificial tears every 6 hours (2 drops) will also be followed by sterile eye ointment and adhesive tape on the eye. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Undecided - It is not yet known if there will be a plan to make this available