<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20180519039722N2</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2020-02-11</date_registration>
      <primary_sponsor>Islamic Azad University</primary_sponsor>
      <public_title>comparison the effect of black tea and green tea on salivary PH after acidic changes</public_title>
      <acronym></acronym>
      <scientific_title>comparison the effect of black tea and green tea on salivary PH after acidic changes between dentistry student of Islamic Azad university</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2020-02-11</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>14</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/44224</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: N/A, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Other design features: The study was designed as a non-randomized study in which 14 study participants were tested each time as a different intervention group, Blinding description: people who participate in study are completely aware about method and steps of study and
The single blindness  of the study is that the numbers are read and recorded by the laboratory expert.</study_design>
      <phase>N/A</phase>
      <hc_freetext>The effect of black and green tea drinks on the pH of saliva after acidic changes.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group:  After preparation of 10% sucrose mouthwash by applying 20 g of sucrose powder to 200 ml of boiling kettle water to 10% concentration.Samples were then taken to 20 ml of mouthwash for one minute and the pH of the saliva was measured. Then rinse the Golestan black sachet with the factory order (put one sachet in a cup and add boiling water and wait 3 to 5 minutes) and drink for 1 minute after cooling.  And then, at intervals (immediately, 5, 10 and 15 minutes), the pH of the saliva was measured by the researcher using a digital PH meter. Intervention 2: Intervention group:  After preparation of 10% sucrose mouthwash by applying 20 g of sucrose powder to 200 ml of boiling kettle water to 10% concentration. Samples were then taken to 20 ml of mouthwash for one minute and the pH of the saliva was measured.Then rinse the Golestan green sachet with the factory order (put one sachet in a cup and add boiling water and wait 3 to 5 minutes) and drink for 1 minute after cooling.  And then, at intervals (immediately, 5, 10 and 15 minutes), the pH of the saliva was measured by the researcher using a digital PH meter. Intervention 3: Control group: Control group: After preparation of 10% sucrose mouthwash by applying 20 g of sucrose powder to 200 ml of boiling kettle water to 10% concentration. Samples were then taken to 20 ml of mouthwash for one minute and the pH of the saliva was measured.  then the sample drinks boiled kettle water for one minute, and then at intervals (5, 10, and 15 minutes intervals)  the pH of the saliva by the researcher is measured by the digital PH meter.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Undecided - It is not yet known if there will be a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for indecision in sharing IPD is no more information</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Saba Aghaei</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>No.4 ,Tenth Neyestan Ave, Pasdaran Ave, Tehran</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>19585/175</zip>
        <telephone>+98 21 2276 3459</telephone>
        <email>s_aghaei@dentaliau.ac.ir</email>
        <affiliation>Islamic Azad University</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Saba Aghaei</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>No.4 ,Tenth Neyestan Ave, Pasdaran Ave, Tehran</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>19585/175</zip>
        <telephone>+98 21 2276 3459</telephone>
        <email>s_aghaei@dentaliau.ac.ir</email>
        <affiliation>Islamic Azad University</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>dentistry student between 20 to 30 years</inclusion_criteria>
      <agemin>20 years</agemin>
      <agemax>30 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria>every one who has effective systemic disease
every one who has xerostomia
every one who has different diet
every one who smoke
every one who has periodontal disease
every one who use affective drugs on saliva
every one who use orthodontic appliance or removable denture
every one who receive topical floride in last 2 weeks
every one who use floride mouthwash in last 3 weeks</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code></hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword></hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Prevention</i_code>
      <i_code>Prevention</i_code>
      <i_code>Prevention</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group:  After preparation of 10% sucrose mouthwash by applying 20 g of sucrose powder to 200 ml of boiling kettle water to 10% concentration.Samples were then taken to 20 ml of mouthwash for one minute and the pH of the saliva was measured. Then rinse the Golestan black sachet with the factory order (put one sachet in a cup and add boiling water and wait 3 to 5 minutes) and drink for 1 minute after cooling.  And then, at intervals (immediately, 5, 10 and 15 minutes), the pH of the saliva was measured by the researcher using a digital PH meter.</i_keyword>
      <i_keyword>Intervention group:  After preparation of 10% sucrose mouthwash by applying 20 g of sucrose powder to 200 ml of boiling kettle water to 10% concentration. Samples were then taken to 20 ml of mouthwash for one minute and the pH of the saliva was measured.Then rinse the Golestan green sachet with the factory order (put one sachet in a cup and add boiling water and wait 3 to 5 minutes) and drink for 1 minute after cooling.  And then, at intervals (immediately, 5, 10 and 15 minutes), the pH of the saliva was measured by the researcher using a digital PH meter.</i_keyword>
      <i_keyword>Control group: Control group: After preparation of 10% sucrose mouthwash by applying 20 g of sucrose powder to 200 ml of boiling kettle water to 10% concentration. Samples were then taken to 20 ml of mouthwash for one minute and the pH of the saliva was measured.  then the sample drinks boiled kettle water for one minute, and then at intervals (5, 10, and 15 minutes intervals)  the pH of the saliva by the researcher is measured by the digital PH meter.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>The effect of black and green tea drinks on the pH of saliva after acidic changes. Timepoint: Measurement of pH before intervention, immediately after sucrose mouthwash, immediately after tea drink and at 5,10,15 min after drink. Method of measurement: Digital PH meter.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Islamic Azad University</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2019-05-11</approval_date>
        <contact_name>Ethics committee of Tehran Islamic Azad University of Dental Branch of Medical Sciences</contact_name>
        <contact_address>No. 4, Tenth Neyestan, Pasdaran Ave, Tehran Tehran Tehran Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
