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IRCT138903254191N1 IRCT 2011-01-09 Atieh comprehensive psyche and nerve center Repetitive transcranial magnetic stimulation and intermittent theta burst stimulation in schizophrenia The Comparison of effectiveness of repetitive TMS and iTBS on negative Symptoms and Cognition in Patients with Schizophrenia:a study randomized and double blind 2011-01-05 anticipated 30 Complete https://irct.ir/trial/4418 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. N/A Schizophrenia. Intervention 1: 15 Hz rTMS are applied during 20 to 30 minutes in 20 sessions. Intervention 2: 50Hz theta burst ia applied during 5 to 10 minutes in 20 sessions. Intervention 3: Sham coil in 20 sessions.
public
scientific Reza Kazemi
Faculty of Psychology & Education University of Tehran Jalal Al-e-Ahmad Ave. Tehran, Iran,P.O. Box 11455/6456
tehran Iran (Islamic Republic of) +98 21 8401 2128 rezakazemi@ut.ac.ir University of Tehran Iran (Islamic Republic of) Iran (Islamic Republic of) Inclusion Criteria: outpatients male and female with the range of 18-50 years of age, The diagnosis of Schizophrenia according to DSM-IV-TR, Completion of Consent Form, Being Under Supervision of a psychiatrist, being able to adhere to treatment Schedule, having stable symptoms as defined by not requiring a change in Antipsychotic medication for at least 4 weeks or at least 2 weeks for psychotropic agents prior to entering the Study Exclusion Criteria: The history of rTMS treatment for any reason, Intracranial Implant and other ferromagnetic materials close to the head, Cardiac Pacemaker, drug Pumps, acute heart attack, the risk of Seizure with any reasons, high Intracranial pressure, The history of epilepsy or Seizure in the first relatives, any metal in Head, brain trauma, history of loss of consciousness for more than 5 minutes, pregnancy, breastfeeding, drug dependency, high risk of Suicide, significant positive symptoms 18 years 50 years Both F20 Schizophrenia Treatment - Devices Treatment - Devices Placebo 15 Hz rTMS are applied during 20 to 30 minutes in 20 sessions 50Hz theta burst ia applied during 5 to 10 minutes in 20 sessions Sham coil in 20 sessions Negative symptoms. Timepoint: Session One,Session ten, Session twenty. Method of measurement: Positive and negative symptom scale. Cognitive functioning. Timepoint: Sessions One, ten, and twenty. Method of measurement: Neuropsychology Battery Tests. Depression. Timepoint: Session One,Session ten, Session twenty. Method of measurement: Calgary depression for schizophrenia scale (CDSS). Quality of life. Timepoint: Session One,Session ten, Session twenty. Method of measurement: Schizophrenia quality of life scale (SQLS). Social Functioning. Timepoint: Sessions One, ten, and twenty. Method of measurement: Social and occupational functioning Assessment scale (SOFAS). Atieh comprehensive psyche and nerve center Approved 2010-11-07 University of Social wellfare and rehabilitation sciences University of Social Wellfare and Rehabilitation Sciences, Kodakyar St, Evin, Tehran, Iran. Tehran Iran (Islamic Republic of)