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IRCT20140921019250N2 IRCT 2020-02-20 Tabriz University of Medical Sciences The effect of continuous heparin infusion on the duration of central venous catheter patency in preterm infants The effect of continuous heparin infusion on the duration of open peripheral central venous catheter (PICC) patency in preterm neonates 2018-03-21 anticipated 126 Complete https://irct.ir/trial/44166 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study, all patients will be given a code and all codes will be randomly divided into two groups using randomization software. Only the person responsible for collecting the patient information and results were aware of this coding, Blinding description: Patient information will be provided by the treating physician as well as the type of treatment and the type of each patient's coding, and only one person who is responsible for collecting study results and data and has no role in the treatment will know the coding. Treatment will also be provided to each individual in similar containers by a person responsible for collecting study results and data that does not play a role in the treatment coded. 4 Premature babies. Intervention 1: Intervention group: The study group (administration of intravenous fluids containing 0.5 U / ml / hr) will receive two dextrose-based injections containing amino acid and lipid. Unbroken heparin will also be used. Intervention 2: Control group: The study group (administration of intravenous fluids containing dextrose serum at a dose of 0.5 U / ml / hr) will receive two dextrose-based injections containing amino acid and lipid. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is It is under investigation.
public Dr Majid Mahallei
Faculty of Medicine, Tabriz University of Medical Sciences, Daneshgah Street, Tabriz.
Tabriz Iran (Islamic Republic of) 0 +98 41 3385 1949 medicalresearchtbz@gmail.com Tabriz University of Medical Sciences scientific Majid Mahallei
Children Hospital of Tabriz University of Medical Science, Sheshgelan Street, Tabriz, Eastern Azerba
Tabriz Iran (Islamic Republic of) 0 +98 41 3385 1949 mahalleim@tbzmed.ac.ir Tabriz University of Medical Sciences Iran (Islamic Republic of) All premature infants (gestational age less than 34 weeks) admitted to NICU ward of Alzahra hospital in Tabriz who require PICC catheter insertion no limit 9 months Both Infants with a bleeding tendency Grade 3 and 4 intravascular hemorrhage Newly diagnosed sepsis Thrombocytopenia DIC arrhythmia Congenital malformations Increased PTT (more than 71 seconds) Babies in need of heparin Babies in need of heparin P07.3 Preterm [premature] newborn [other] Treatment - Drugs Treatment - Drugs Intervention group: The study group (administration of intravenous fluids containing 0.5 U / ml / hr) will receive two dextrose-based injections containing amino acid and lipid. Unbroken heparin will also be used. Control group: The study group (administration of intravenous fluids containing dextrose serum at a dose of 0.5 U / ml / hr) will receive two dextrose-based injections containing amino acid and lipid. Duration of catheter use is the time between insertion and exit of the catheter due to obstruction. Timepoint: On the first and seventh day, and immediately after the catheter was removed. Method of measurement: Sonography. Tabriz University of Medical Sciences Approved 2019-09-27 Tabriz University of Medical Sciences. Daneshgah Street Tabriz North Khorasan Iran (Islamic Republic of)