]>
IRCT20101211005362N23 IRCT 2020-03-25 Esfahan University of Medical Sciences oral celecoxib on shivering during and after orthopedic lower extremity surgery spinal A Comparison of the preventive effect of 100 mg and 200 mg oral celecoxib on shivering during and after orthopedic lower extremity surgery under the spinal anesthesia in patients and the control group 2016-05-21 anticipated 105 Complete https://irct.ir/trial/44003 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Random Allocation. Numbered balls from 1 to 105 were put in a box. Then were pulled out randomly and the number was written in a group of Celecoxib 100 mg, Celecoxib 200 mg and placebo, respectively. Each number represented the order of patients entry to the hospital and had the entrance requirements and had given the consent for entering to the study, Blinding description: بي حسي نخاعي در فضاي L3-L4با ماركائين 5/0% با سوزن 22G Quincke spinal انجام گرفت.كپسول‌هاي celecoxib با كد خاص 3 ساعت قبل از SA به بيمار داده ‌شد. اين كار توسط متخصص بيهوشي اول انجام و داده‌ها توسط متخصص بيهوشي دوم از طريق پرسشنامه جمع‌آوري و بدين طريق كورسازي صورت مي‌گرفت. 2-3 pain. Intervention 1: First intervention group: received Celecoxib 100mg three hours before operation. Intervention 2: Second intervention group: received Celecoxib 200mg three hours before operation. Intervention 3: Control group: received placebo three hours before operation. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Nothing to declare
public Seyed Mohamadreza Safavi
Anesthesiology Office, Alzahra Hospital, Sofeh Ave
Isfahan Iran (Islamic Republic of) 8174675731 +98 31 3620 1992 safavi@med.mui.ac.ir Esfahan University of Medical Sciences scientific Seyed Mohamadreza Safavi
Anesthesiology Office, Alzahra Hospital, Sofeh Ave
Isfahan Iran (Islamic Republic of) 8174675731 +98 31 3620 1992 safavi@med.mui.ac.ir Esfahan University of Medical Sciences Iran (Islamic Republic of) the patients with American Society of Anesthesiologists (ASA) 1 age between 18 and 65 18 years 65 years Both History of hypertension Sever cardiovascular disease Allergy to Coxib drugs Psychological disorder based on history Temperature less than 36 or more than 38 Celsius degree Usage of alcohol and opioids Usage of vasodilators Allergy to Aspirin T88.51 Hypothermia following anesthesia Treatment - Drugs Treatment - Drugs Treatment - Drugs First intervention group: received Celecoxib 100mg three hours before operation. Second intervention group: received Celecoxib 200mg three hours before operation. Control group: received placebo three hours before operation. Incidence and severity of shivering based on Tsai and Cha scale. Timepoint: every 15 minutes. Method of measurement: objective. Esfahan University of Medical Sciences Approved 2017-05-21 Ethics committee of Isfahan University of Medical Sciences Isfahan university of medical science, Isfahan, Iran isfahan Isfehan Iran (Islamic Republic of)