]>
IRCT20191126045514N1 IRCT 2021-02-14 Tarbiat modares University The effect of turmeric on the treatment of women with polycystic ovary syndrome The survery of Turmeric Extract effect on Serum Adiponectin Levels and the FerrimanGallwey Scoring System of Hirsutism in PCOS Women; a Randomized Double-blind ClinicalTrial 2019-12-30 anticipated 20 Complete https://irct.ir/trial/43821 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization of an individual with an envelope in dividing the groups into two groups A and B. In this method, we selected a number of cards or letters as the intervention group and the same number of cards for the control group, then merged the cards together. One card was taken out and its allocation was recorded, and after the card was taken out, we returned it again to all the other cards. Then the cards are merged again and we take out another card. This process continues until a random sequence is reached according to the sample size, Blinding description: The present study is a double-blind study and the researcher and the patient will be unaware of the treatment and grouping of the study. For this purpose, turmeric extract and placebo are encoded by a third party. The main researcher intervenes patients in a double-blind manner based on the code of drug packages. The drug code is recorded on the demographic information completion form. Intervention in the PCOS target group will be using the usual treatment (metformin) with turmeric extract for 8 weeks at a rate of 100 kg / mg Placebo will be prepared in a similar way to turmeric extract without its effective ingredients. 8 weeks after using turmeric extract, again in women of both groups A venous blood sample will be taken. 2 PCOS. Intervention 1: Intervention group: The usual treatment (metformin) with turmeric extract will be 100 mg / kg for 8 weeks. This article has been extracted and concentrated by Dr. Elaheh Sadeghi under the supervision of Dr. Mohsen Sharifi, Professor, Department of Plant Physiology, Faculty of Basic Sciences, Tarbiat Modarres University, Iran. Intervention 2: Control group: the usual treatment (metformin) and placebo, Placebo will be prepared in a similar way to turmeric extract without its effective ingredients. 8 weeks after using , women in both groups will have venous blood sampling again. Yes - There is a plan to make this available What will be shared: Only part of the information When: Start of access period 6 months after printing results To whom: Researchers working in academic and scientific institutions Conditions: Scientific and research studies Where to obtain: Mobarakeh.mazareei@modares.ac.ir mobarakeh72mazareei@gmail.com How to obtain: one week until one month Comments:
public Najmeh Tehranian
Tehran, Jalal Al Ahmad, Paul Nasr, Tarbiat Modarres University
TEHRAN Iran (Islamic Republic of) 111-14115 +98 21 8800 6544 tehranian@modares.ac.ir tarbiat modares university scientific Najmeh tehranian
Tehran, Jalal Al Ahmad, Paul Nasr, Tarbiat Modarres University
tehran Iran (Islamic Republic of) 111-14115 +98 21 8800 6544 tehranian@modares.ac.ir tarbiat modares university Iran (Islamic Republic of) Age range 35-18 years Be Iranian and Persian language  Satisfaction of the person to enter the study Without any history of abortion and cesarean delivery No medical problems such as diabetes and high blood pressure, psychological diseases, infections and other pelvic pathologies and other medical problems. Have spent the past six months without severe psychological stress Diagnosis of polycystic ovary syndrome based on Rotterdam criteria and approval by a gynecologist No alcoholism and no history of alcohol and drug use The diet is normal. 18 years 35 years Female A person with polycystic ovary disease is taking a drug other than metformin E28.2 Polycystic ovarian syndrome Treatment - Drugs Placebo Intervention group: The usual treatment (metformin) with turmeric extract will be 100 mg / kg for 8 weeks. This article has been extracted and concentrated by Dr. Elaheh Sadeghi under the supervision of Dr. Mohsen Sharifi, Professor, Department of Plant Physiology, Faculty of Basic Sciences, Tarbiat Modarres University, Iran Control group: the usual treatment (metformin) and placebo, Placebo will be prepared in a similar way to turmeric extract without its effective ingredients. 8 weeks after using , women in both groups will have venous blood sampling again. Serum adiponectin levels. Timepoint: Befor and 8 WEEKS After intervention. Method of measurement: Blood Test. Hirsutism status based on Freeman Galloway score. Timepoint: Befor and 8 WEEKS After intervention. Method of measurement: View and score based on Freeman Galloway score. Tarbiat modares University Approved 2019-12-29 Ethics committee of Tarbiat modares University Tehran jalal al ahmad Ave tarbiat modares university TEHRAN Tehran Iran (Islamic Republic of)