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IRCT20130722014106N7 IRCT 2019-12-24 Kermanshah University of Medical Sciences Effect of semi-solid form ofextract of chamomile, Thymus vulgaris L and Oliveria decumbens on osteoarthritis pain. Efficacy of semi-solid form of extract of chamomile, Thymus vulgaris L and Oliveria decumbens to relieve osteoarthritis pain in patients with osteoarthritis. 2019-12-01 anticipated 102 Complete https://irct.ir/trial/43759 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Block randomization will be determined online using the sealedenvelope.com site, blocks and allocation modes. This is based on a sample size of 102 patients with 3 treatment groups (group I cream (A), group II gel (B) and group III, placebo (C)), the blocks are considered to be 6 (6 persons per block), with a total of 17 blocks of 6 persons. For example a few blocks below. Patients in this study would not be aware of medication or placebo. Block 1: BACABC Block 2: AABCCB Block 3: CCABAB And , Blinding description: To blind the study, the drugs and placebo were designed to be exactly similar in color, odor and concentration, and the physician and the patient could not discern whether patients were taking the drug or the placebo; And only the researcher and the data collector are aware that the patient has used the drug or the placebo. 3 Osteoarthritis Pains. Intervention 1: Intervention group I : This group of patients with osteoarthritis pain, uses cream containing 15% of 3 plant extracts blend in cream base. The patient should use the cream 3 times a day for 3 weeks and complete the questionnaire each week. Intervention 2: Intervention group II: This group of patients with osteoarthritis pain, uses gel. Includes: 3 Plant Extracts Blend 15% in gel base. The patient should take the drug 3 times a day for 3 weeks and complete the questionnaire each week. Intervention 3: Control group: This group of patients with osteoarthritis pain, uses placebo cream and gel, which contains all the ingredients of cream and gel, except for the mixture of 3 plant extracts blend. The patient should take the drug 3 times a day for 3 weeks and complete the questionnaire each week. Yes - There is a plan to make this available What will be shared: All data can be shared in the form of scores from patient completed questionnaires. When: 6 months after printing the results. To whom: Researchers working in academic institutions. Conditions: They are only allowed to study the data and use it as a source. Where to obtain: Kermanshah University of Medical Sciences Sayyed Milad Mousavi Mehr miladmosavi8977@gmail.com How to obtain: Once they have sent the email and registered the request, they will be sent. Comments:
public Dr. Reza Tahvilian
School of Pharmacy, Nursing Blvd., University Ave., Shahid Shiroudi Blvd., Kermanshah
Kermanshah Iran (Islamic Republic of) 6714415153 +98 83 3427 6489 rtahvilian@kums.ac.ir Kermanshah University of Medical Sciences scientific Dr. Reza Tahvilian
School of Pharmacy, Nursing Blvd., University Ave., Shahid Shiroudi Blvd., Kermanshah
Kermanshah Iran (Islamic Republic of) 6714415153 +98 83 3427 6489 rtahvilian@kums.ac.ir Kermanshah University of Medical Sciences Iran (Islamic Republic of) Patients with osteoarthritis have stage 1 and 2 disease.. Patient satisfaction to participate in the study. no limit no limit Both Other underlying diseases that interfere with the study of the effect of the drug. Pregnant women and lactating women. Addicts (natural opiates, synthetics or alcohol). M17 Osteoarthritis of knee Treatment - Drugs Treatment - Drugs Placebo Intervention group I : This group of patients with osteoarthritis pain, uses cream containing 15% of 3 plant extracts blend in cream base. The patient should use the cream 3 times a day for 3 weeks and complete the questionnaire each week. Intervention group II: This group of patients with osteoarthritis pain, uses gel. Includes: 3 Plant Extracts Blend 15% in gel base. The patient should take the drug 3 times a day for 3 weeks and complete the questionnaire each week. Control group: This group of patients with osteoarthritis pain, uses placebo cream and gel, which contains all the ingredients of cream and gel, except for the mixture of 3 plant extracts blend. The patient should take the drug 3 times a day for 3 weeks and complete the questionnaire each week. Evaluation of the effect of medication on osteoarthritis pain by the score of completing a questionnaire delivered to the patient. Timepoint: Symptoms of pain relief are at 7, 14 and 21 days after starting medication. Method of measurement: How to measure the efficacy of the drug is determined by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire completed by the patient. Kermanshah University of Medical Sciences Approved 2019-09-17 Ethics Committee of Research in Kermanshah University of Medical Sciences School of Pharmacy, Nursing Blvd., University Ave., Shahid Shiroudi Blvd., Kermanshah Kermanshah Kermanshah Iran (Islamic Republic of)