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IRCT20191113045428N1 IRCT 2019-12-19 Gorgan University of Medical Sciences Aloe vera in periodontits Assessment of the effect of local application of Aloe vera gel as an non-surgical adjunctive treatment in patients with chronic periodontitis 2019-12-21 anticipated 22 Recruiting https://irct.ir/trial/43616 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The procedure will be split mouth in such a way that randomly with a pre-arranged randomization by random number table list half of the jaw is treated only with scaling and root planing and the other half with scaling and root planing with Topical use of aloe vera gel will be. After gel application, all treated areas will be covered with periodontal dressing for 24 hours. The purpose of periodontal dressing in the test areas is to prevent the saliva from gaining gel and in the control areas to blind the patient, Blinding description: The participant is kept blind as he does not know which quadrant of the jelly is placed because all the parts are put on periodontal dressing.The measuring clincian is kept blind and does not know where the gel is inserted when measuring the parameters. 3 Chronic periodontitis is an inflammatory periodontal disease caused by the penetration of germs into the inflamed gums, resulting in periodontal tissue destruction and alveolar bone loss. Chronic periodontitis is the most common form of periodontitis.. Intervention 1: Intervention group: Before starting treatment, patients are subjected to the same hygiene training and are asked to use Orchid floss twice a day to clean interdental surfaces, followed by bass technique and Dr.West (soft) tooth brushing and toothpaste Merident Brush their teeth.A week later clinical parameters, measurements and treatment will begin.The procedure will be split mouth.That is, it will be randomly treated with a pre-made randomization list of half of a jaw under scaling and root planing with Aloe vera gel will be treated twice a week with topical application. Intervention 2: Control group: Before starting treatment, patients are subjected to the same hygiene training and are asked to use Orchid floss twice a day to clean interdental surfaces, followed by bass technique and Dr.West (soft) tooth brushing and toothpaste Merident Brush their teeth.A week later clinical parameters, measurements and treatment will begin.The procedure will be split mouth. In the control group the other half of the jaw is treated only with scaling and root planing.In fact, the effectiveness of a substance is measured by each individual. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is The study will be decided by the research team after the study is published.
public Shaghayegh Vadoudi
Dental clinic, Edalat 97 Ave., Naharkhoran Blvd.
Gorgan Iran (Islamic Republic of) 4916953358 +98 17 3255 0565 Vadodi.sh@goums.ac.ir Gorgan University of Medical Sciences scientific Ida Mirzaei
Dental clinic, Edalat 97 Ave., Naharkhoran Blvd.
Gorgan Iran (Islamic Republic of) 4916953358 +98 17 3255 0565 Drmirzaei.a@goums.ac.ir Gorgan University of Medical Sciences Iran (Islamic Republic of) Being over 18 years old Having at least 20 teeth in the mouth Having at least one area with probing depth of 4 mm or more in at least two quadrants Having at least one area of clinical attachment loss of 3 mm or more in at least two quadrants Necessity to be available during the research process Having informed consent 18 years no limit Both The presence of systemic disease affecting periodontal status Sensitivity to aloe vera and its products Receive systemic or topical antibiotic therapy in the past 3 months Antioxidants intake of vitamin C or E in the past 3 months Scaling and root planing treatment in the past 6 months Smoking Alcohol consumption Pregnancy and lactation K05.3 Chronic periodontitis Treatment - Drugs Treatment - Devices Intervention group: Before starting treatment, patients are subjected to the same hygiene training and are asked to use Orchid floss twice a day to clean interdental surfaces, followed by bass technique and Dr.West (soft) tooth brushing and toothpaste Merident Brush their teeth.A week later clinical parameters, measurements and treatment will begin.The procedure will be split mouth.That is, it will be randomly treated with a pre-made randomization list of half of a jaw under scaling and root planing with Aloe vera gel will be treated twice a week with topical application. Control group: Before starting treatment, patients are subjected to the same hygiene training and are asked to use Orchid floss twice a day to clean interdental surfaces, followed by bass technique and Dr.West (soft) tooth brushing and toothpaste Merident Brush their teeth.A week later clinical parameters, measurements and treatment will begin.The procedure will be split mouth. In the control group the other half of the jaw is treated only with scaling and root planing.In fact, the effectiveness of a substance is measured by each individual Probing Pocket Depth. Timepoint: Before starting the study, 1 and 3 months later. Method of measurement: Distance of free gingival margin to base of gingival groove by periodontal probe Williams. Clinical Attachment Loss. Timepoint: Before starting the study, 1 and 3 months later. Method of measurement: Distance of Cemento Enamel Junction to base of gingival groove by periodontal probe Williams. Gingival Index. Timepoint: Before starting the study, 1 and 3 months later. Method of measurement: Specified number to determine the degree: Gingival Index0 (normal), Gingival Index1 (mild), Gingival Index2 (medium), Gingival Index3 (severe). Plaque Index. Timepoint: Before starting the study, 1 and 3 months later. Method of measurement: Percentage of adherent microbial plaque on tooth surface: Desirable: 0-30 Average: 31-50 Undesirable: 51-100. Gorgan University of Medical Sciences Approved 2019-11-11 Ethics committee of Golestan University of Medical Sciences Dental clinic, Edalat 97 Ave., Naharkhoran Blvd. Gorgan Golestan Iran (Islamic Republic of)