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IRCT20120909010795N5 IRCT 2021-05-31 Shiraz University of Medical Sciences Comparison of the Effectiveness of Microneedling Therapy with CO2 Fractional Leaser therapy for theTreatment of Striae Distensa in Patients with Striae Distensae Comparison of the Effectiveness of Microneedling Therapy with CO2 Fractional Leaser therapy for theTreatment of Striae Distensa in Patients with Striae Distensae 2019-04-07 anticipated 40 Complete https://irct.ir/trial/43538 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: Two common treatment modalities are discussed in this study, Randomization description: Each side will be randomly assigned to the treatment method using the "coin flip” method. The microneedling method will be performed with the probability of a "Tail" and the fractional CO2 laser method with the probability of a "Head", Blinding description: Treatment evaluations and scorings will be provided by two non-therapeutic dermatologists. Due to the different nature of treatment, the therapist and the patient are not blind, but the evaluators are blind and unaware of the treatment process. 3 Striae rubra- striae alba. Intervention 1: Intervention group 1: It will be treated with microneedling method on a monthly basis. Intervention 2: Intervention group 2: It will be treated with fractional CO2 laser method on a monthly basis. Yes - There is a plan to make this available What will be shared: Demographic data and clinical trial results When: 6 months later To whom: Researchers Conditions: After publication of the extracted article of the clinical trial Where to obtain: Sending email to the researchers How to obtain: Sending the request via the email Comments:
public Farzaneh Rahimi
Zand street
Shiraz Iran (Islamic Republic of) 14336 - 71348 +98 71 3235 2559 raahimi.1365@gmail.com Shiraz University of Medical Sciences scientific Dr.Nasrin Saki
Zand street
Shiraz Iran (Islamic Republic of) 14336 - 71348 +98 71 3235 2559 sakina@sums.ac.ir Shiraz University of Medical Sciences Iran (Islamic Republic of) Patients older than 15 and less than 50 years Patients with striae including striae alba and striae rubra on abdomen, buttock, and flank lesions Patients had not received previous treatment for striae distance in the last two months 15 years 50 years Both Pregnant women breastfeeding mothers Patients taking immunosuppressive drugs Patients who are prone to forming keloid Patients who have received previous treatment for SD in the past 2 months Patients with Cushing's Syndrome or connective tissue diseases Patients who have vitamin derivatives A used up to 2 months prior to the study Patients who had a history of systemic or topical steroid use, filler injection, abdominal dermabrasion, or laser skin resurfacing in the striae distance area for the past 6–12 months Patients who had striae on their chest or arm Patients with defective blood supply or diabetes mellitus or wound healing disorders L90.6 Linear dermal scars accompanied by epidermal atrophy that affects skin that is subjected to continuous streching. They usually do not cause any significant medical problems, only cosmetic problems. Treatment - Other Treatment - Other Intervention group 1: It will be treated with microneedling method on a monthly basis. Intervention group 2: It will be treated with fractional CO2 laser method on a monthly basis. Dermatologist assessed improvement score. Timepoint: At baseline and 1 and 6 months after treatment. Method of measurement: Photography. Shiraz University of Medical Sciences Approved 2019-02-18 Ethics committee of Shiraz University of Medical Sciences Zand Shiraz Fars Iran (Islamic Republic of)