]>
IRCT20170619034621N3 IRCT 2020-02-01 Vice chancellor for research of Shahid Rajaiee Heart Center Ticagrelor in ST elevation MI Comparing the protective effect of Ticaglerol versus Clopidogrel on Myocardial resistance index in patients with ST elevation myocardial infarction. 2020-03-05 anticipated 35 Complete https://irct.ir/trial/43174 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Block randomization method with block size of 4 will be done. 2 Aacut ST elevation myocardial infarction. Intervention 1: Intervention group: prescribed 180 mg ( two tablet) Ticagrelor orally as a loading dose before stent deployment in cath lab. Intervention 2: Control group: prescribed 600 mg (8 tablet) clopidogrel orally as a loading dose before stent deployment in cath lab. Yes - There is a plan to make this available What will be shared: patient demographic data and the primary and secondary endpoint data When: no limitation To whom: all persons Conditions: no limitation Where to obtain: connect with email:a.mozayani@umsha.ac.ir or research center of Shaheed rajaiee hospitsl How to obtain: after receiving the request for accessibility to data,it was reviewing with research expert and then referred to the master of research Comments:
public Bahram Mohebi
Hashemi rafsanjani highway
Tehran Iran (Islamic Republic of) 1995614331 +98 21 23921 roodbar@yahoo.com Iran University of Medical Sciences scientific Bahram Mohebi
Hashemi rafsanjani highway
Tehran Iran (Islamic Republic of) 1995614331 +98 21 23921 roodbar@yahoo.com Iran University of Medical Sciences Iran (Islamic Republic of) age > 18 years presented with STEMI suitable infarcted related artery for angioplasty patient satisfaction 18 years no limit Both More than single vessel involvement in angiography unprotected leftmain lesion stent thrombosis presentation with cardiogenic shock history of CVA history of MI contraindication of adenosine High degree AV block TIMI flow < 3 at the end of the angioplasty patient dissatisfaction I21 ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction Treatment - Drugs Treatment - Drugs Intervention group: prescribed 180 mg ( two tablet) Ticagrelor orally as a loading dose before stent deployment in cath lab Control group: prescribed 600 mg (8 tablet) clopidogrel orally as a loading dose before stent deployment in cath lab Intramyocardial resistance. Timepoint: immediately after procedure. Method of measurement: QFR software. Left ventricle ejection fraction. Timepoint: during first 24 hours and 3 month after procedure. Method of measurement: echocardiography. Wall motion score index. Timepoint: during first 24 hours and 3 month after procedure. Method of measurement: echocardiography. - Approved 2020-01-25 Shahid rajaiee hospital Hashemi rafsanjani highway Tehran Tehran Iran (Islamic Republic of)