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IRCT20190219042753N1 IRCT 2020-08-21 Islamic Azad University The effect of Gabapentin on the pain after inguinal hernia repair surgery Evaluation the effect of Gabapentin on the pain after inguinal hernia repair surgery in general anesthesia 2020-08-31 anticipated 60 Complete https://irct.ir/trial/43075 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: The computerized block randomization (block sizes of 4 and 6) will carried out in this study. An independent clinical epidemiologist, who will not involved in the conduct of the study used a computerized block randomization program (STATA14 software) uses to produce the allocation codes.The randomization sequences will be concealed in lightproof, sealed envelopes.The research assistant opened sealed, numbered, opaque envelopes containing allocation codes. The eligible participants will be randomized to two equal groups (gabapentin or placebo) according to the randomization list after signing informed consent form, Blinding description: Patients will not be aware of the type of medication they receive and the second executor of the research project will complete the questionnaire at the end of the treatment without knowledge of the two groups. Also the data will be analyzed without any information about group selection. 2-3 Indirect inguinal hernia. Intervention 1: Intervention group: Gabapentin capsules (Caspian Drug Company of Rasht) with a dose of 400 mg will be prescribed as a single dose one hour before surgery. Intervention 2: Control group: The placebo capsule with the same shape and size as the gabapentin capsule containing starch powder will be prescribed one hour before surgery. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information
public Farzaneh Rahchamani
University Blvd - Shahrud Islamic Azad University
Shahroud Iran (Islamic Republic of) 3619943189 +98 23 3239 4530 Farzaneh.rah.chamani.2020@gmail.com Islamic Azad University scientific Farzaneh Rahchamani
University Blvd, Shahrud Islamic Azad University
Shahroud Iran (Islamic Republic of) 3619943189 +98 23 3239 4530 Farzaneh.rah.chamani.2020@gmail.com Islamic Azad University Iran (Islamic Republic of) Unilateral indirect inguinal hernia Consent to enter the study Indication of hernia repair surgery under general anesthesia 20 years 60 years Male Coagulation disorders Psychological and memory disorders Height less than 145 cm Weight more than 100 kg History of alcohol or drug abuse History of taking antacid drugs containing aluminum and magnesium Known allergy to gabapentin K40.90 Unilateral inguinal hernia, without obstruction or gangrene, not specified as recurrent Treatment - Drugs Treatment - Drugs Intervention group: Gabapentin capsules (Caspian Drug Company of Rasht) with a dose of 400 mg will be prescribed as a single dose one hour before surgery. Control group: The placebo capsule with the same shape and size as the gabapentin capsule containing starch powder will be prescribed one hour before surgery. Pain after surgery. Timepoint: One and eight hours after surgery. Method of measurement: Visual Analogue Scale. Complications of anesthesia include nausea and vomiting. Timepoint: One and eight hours after surgery. Method of measurement: Asking from patient and recording in the checklist. Duration of hospitalization. Timepoint: At the time of discharging. Method of measurement: Checking the file and recording in the checklist. Islamic Azad University Approved 2018-01-02 Ethics committee of Islamic Azad University of Shahrood No.1, Jirudi Ave., Sani Blvd., Narmak shahrood Semnan Iran (Islamic Republic of)