IRCT20190325043111N1 IRCT 2019-10-28 Esfahan University of Medical Sciences Assessment of two doses of Alendronate on the treament of osteopenia on menopaused females The effect of two different doses of Alendronate on the treatment of osteopenia based on fracture risk assessment (FRAX) in menopauses women who referred to Alzahra hospital during 2014-17 2014-04-04 anticipated 140 Complete https://irct.ir/trial/43014 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization; individual; using Random allocation software as those with odd number are allocated to one and with even number to the other group, Blinding description: The clinical investigator who evaluates FRAX index will be blinded. 2-3 Osteopenia. Intervention 1: Intervention group: Treatment with 70 mg weekly Alendronate for 2 years. Intervention 2: Intervention group: Treatment with 35 mg weekly Alendronate for 2 years. Yes - There is a plan to make this available What will be shared: In this study, patients' densitometry is recorded and they would be followed for two years. Then as they will be followed for a longer duration, the patients'records will be provided only following the connection to the study responsible rheumatologist. When: The data accessibility due to the long-term follow-up is not possible. To whom: Rheumatologist professors Conditions: For long-term follow-up study by the permission of rheumatologist responsible for the study Where to obtain: The rheumatologist responsible for the study How to obtain: It should be connected to the rheumatologist responsible for the study Comments: