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IRCT201111094093N3 IRCT 2011-11-15 Ardabil University of Medical Sciences The effect of ondansetron and metoclopramide on postoperative nausea and vomiting (PONV) in laparoscopic cholecystectomy The effect of ondansetron and metoclopramide on postoperative nausea and vomiting (PONV) in laparoscopic cholecystectomy. 2011-09-23 anticipated 90 Complete https://irct.ir/trial/4288 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention. N/A Nausea and vomiting after laparoscopic cholecystectomy. Intervention 1: Metoclopramide (10 mg, increased volume to 2 ml) before induction of anesthesia. Intervention 2: Ondansetron(4mg, increased volume to 2 ml) before induction of anesthesia. Intervention 3: Normal Saline, 2 ml, before induction of anesthesia.
public Masood Entezariasl
Imam Khomeini Hospital, Ardabil, Iran
Ardabil Iran (Islamic Republic of) +98 45 1225 1688 m.entezari@arums.ac.ir Ardabil University of Medical Sciences scientific Masood Entezariasl
Imam Khomeini Hospital, Ardabil, Iran
Ardabil Iran (Islamic Republic of) +98 45 1225 1688 m.entezari@arums.ac.ir Ardabil University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: Candidate for laparoscopic cholecistectomy, ASA class I-II, age 15-80 years Exclusion criteria: Gastroesophageal reflux - Severe obesity - difficult airway 15 years 80 years Both K91.0 Vomiting following gastrointestinal surgery Prevention Prevention Prevention Metoclopramide (10 mg, increased volume to 2 ml) before induction of anesthesia Ondansetron(4mg, increased volume to 2 ml) before induction of anesthesia Normal Saline, 2 ml, before induction of anesthesia Nausea after surgery. Timepoint: In the recovery room after surgery-6 and 24 hours after surgery. Method of measurement: Observation and history taking of patients, relatives and nursing staff. Vomiting after surgery. Timepoint: In the recovery room after surgery-6 and 24 hours after surgery. Method of measurement: Observation and history taking of patients, relatives and nursing staff. Ardabil University of Medical Sciences Approved 2011-09-08 Ardabil University of Medical Sciences Daneshgah street, Ardabil Ardabil Iran (Islamic Republic of)