IRCT20190824044599N1 IRCT 2019-10-27 Artesh University of Medical Sciences Effect of probiotic administration on male infertility Assessing the effect of probiotic administration on sperm DNA fragmentation, sperm parameters and seminal oxidative stress in men diagnosed with idiopathic infertility 2019-11-22 anticipated 60 Complete https://irct.ir/trial/42872 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: We will recruit permutation block randomization method. Regarding our sample size, 9 blocks containing 8 units (individuals) will be applied. Random sequence will be built on all the possible permutations. Due to our triple blinded design, no allocation concealment will be used, Blinding description: Drug and placebo packings are identical and given to the participants according to randomization sequence. In the present study, health caregivers, researcher(s) in charge of data collection and manuscript drafting, as well as statistical analysis will be blinded. 2-3 Idiopathic male infertility. Intervention 1: Intervention group: Group of patients receiving a single capsule (500 mg) of FamiLact daily (after meal). Each capsule of FamiLact contains bacterial strains of Lactobacillus rhamnosus, Lactobacillus casei, Lactobacillus bulgaricus, Lactobacillus acidophilus, Bifidobacterium breve, Bifidobacterium longum, Streptococcus thermophilus and also 10⁹ CFU of Fructooligosaccharides as prebiotic. FamiLact is a product of Zist Takhmir Pharmaceutical Company, under the permission of Food and Drug department of the Ministry of Health and Medical Education (reference no.: 0347756442342525). Intervention 2: Control group: A group of patients receiving a capsule containing 500 mg of starch per day. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information.