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IRCT20181010041299N2 IRCT 2019-10-31 Shahroud University of Medical Sciences The Effect of Activated Vitamin D on treatment of Acute Kidney injury The Effect of Activated Vitamin D on treatment of Acute Kidney injury 2019-09-23 anticipated 76 Complete https://irct.ir/trial/42110 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients were randomly divided into 38 groups using Random allocation software. The numbered envelopes will be arranged in the order of 1 to 76, respectively, and within each envelope the type of treatment is specified, which will be executed after the treatment envelope is opened, Blinding description: To prevent patient awareness and the analyst of the study, each treatment group will be assigned a code that only the specialist program will know about their interpretation. The code commentary will be announced after analyzing the results. 3 Acute Kidney Failure. Intervention 1: Intervention group: The case group received 0.25 mg rocanrolol tablets, except for routine renal injury treatment. Intervention 2: Control group: patients will receive no medication other than routine treatment of acute kidney injury. Yes - There is a plan to make this available What will be shared: All collected data will be shared after being unidentified and analyzed When: 2020 To whom: For all scholars Conditions: For use in studies Where to obtain: Supervisor How to obtain: By email and correspondence and justification for use Comments:
public Dr. Asie Emmett Mohammadi
Room 409, Third floor, medical School, Shahroud University of Medical Sciences, Hafte-Tir Square, Tehran Avenue, Shahroud, Iran.
Shahroud Iran (Islamic Republic of) ۳۶۱۴۷-۷۳۹۴۷ +98 23 3239 5009 asyomat@gmail.com Shahroud University of Medical Sciences scientific Dr. Monireh Amerian
Room 409, Third floor, medical School, Shahroud University of Medical Sciences, Hafte-Tir Square, Tehran Avenue, Shahroud, Iran.
Shahroud Iran (Islamic Republic of) ۳۶۱۴۷-۷۳۹۴۷ 0098233234200 amerion@shmu.ac.ir Shahroud University of Medical Sciences Iran (Islamic Republic of) Ages over 18 years Acute kidney failure according to KDIGO criteria Having informed consent to participate in the study Hospitalized in the usual ward, ICU CCU of Imam Hossein Shahrood Hospital Non-return of creatinine to normal within 48 hours despite fluid replacement or granular and epithelial casts Ability to eat or own NG Tube No history of kidney disease and kidney transplant No history of taking vitamin D compounds for the past 7 days No active primary parathyroid disease or active granulomatous disease or symptomatic nephrolithiasis in the past 3 months No pregnancy no breastfeeding 18 years no limit Both Get cytochrome p450 inhibitor drugs Hemoglobin less than 7 N17.0 Acute renal failure with tubular necrosis Treatment - Drugs N/A Intervention group: The case group received 0.25 mg rocanrolol tablets, except for routine renal injury treatment. Control group: patients will receive no medication other than routine treatment of acute kidney injury. Evaluation of kidney function. Timepoint: Daily. Method of measurement: blood test. Urea. Timepoint: Daily. Method of measurement: blood test. Creatinine level. Timepoint: Daily. Method of measurement: blood test. Shahroud University of Medical Sciences Approved 2019-08-17 Ethics Committee of Shahroud University of Medical Sciences Room 409. Third floor. medical School. Shahroud University of Medical Sciences. Hafte-Tir Square. Tehran Avenue. Shahroud. Iran Shahroud Semnan Iran (Islamic Republic of)