IRCT20190804044431N1 IRCT 2019-10-18 Iran University of Medical Sciences Compare the effect of TDCS with TENS on osteoarthritis of the knee Comparison of the Therapeutic Effect of Transcutaneous Electrical Nerve Stimulation (TENS) with Transcranial Direct Current Stimulation (TDCS) in Patients with Knee Osteoarthritis 2019-10-12 anticipated 40 Complete https://irct.ir/trial/42035 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Block randomization using sealed envelopes into 2 groups, Blinding description: Person who analyze data, do not know about the distribution of patients to the two treatment groups with Transcutaneous Electrical Nerve Stimulation and Transcranial Direct Current Stimulation. N/A Knee Osteoarthritis. Intervention 1: Intervention group: In this group, patients receive 6 sessions of TDCS treatment ( 2 mA intensity for 20 minutes and two 35cm2 electrodes that anode pole placed at the motor area and cathode pole positioned at the supraorbital area the opposite side of involved knee) 3 times a week combined with knee strengthening exercises (Close kinematic chain type twice a day) which are taught by a physical medicine and rehabilitation specialist. Intervention 2: Control group: In this group, patients receive 6 sessions of TENS treatment (100 Hz conventional TENS and 100 µs pulse width and the intensity of 10% below the patient's motor threshold, for 25 minutes) 3 times a week combined with knee strengthening exercises (Close kinematic chain type twice a day) which are taught by a physical medicine and rehabilitation specialist. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information