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IRCT20150125020795N4 IRCT 2019-10-04 Tabriz University of Medical Sciences The efficacy of intravenous bolus Dexmedetomidine and mepridine on the treatment of shivering following general anesthesia Comparing the efficacy of intravenous bolus Dexmedetomidine and mepridine on the treatment of shivering following general anesthesia 2019-09-23 anticipated 100 Complete https://irct.ir/trial/41905 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients wishing to participate in the study who meet the inclusion criteria will be selected as available sampling and then randomly assigned to two control and intervention groups using Randlist software, Blinding description: An anesthesiologist who evaluates patients' response to the prescribed drug and also patients who are unaware of the type of intervention. 3 Shivering following general anesthesia. Intervention 1: Intervention group: In the intervention group, dexmedomidine (Imagen-Iran) will be used 1 µg / kg body weight. Intervention 2: Control group: The control group will receive 10 mg of pethidine (Exir - Iran). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information.
public Samad Eslam Jamal Golzari
Department of Anesthesiology., Faculty of Medicine., Golgasht Street
Tabriz Iran (Islamic Republic of) 5166614766 +98 41 3334 1994 golzaris@tbzmed.ac.ir Tabriz University of Medical Sciences scientific Samad Eslam Jamal Golzari
Department of Anesthesiology., Faculty of Medicine., Golgasht Street
Tabriz Iran (Islamic Republic of) 5166614766 +98 41 3334 1994 golzaris@tbzmed.ac.ir Tabriz University of Medical Sciences Iran (Islamic Republic of) Patients with ASA grade one or two Age range of 18 to 65 years After surgery, the patient has grade 3 or 4 shivering anesthesia. 18 years 65 years Both Patients under 18 or over 65 years Previous sensitivity to pethidine or dexmedetomidine Patient's low blood pressure T88.5 Other complications of anesthesia Treatment - Drugs Treatment - Drugs Intervention group: In the intervention group, dexmedomidine (Imagen-Iran) will be used 1 µg / kg body weight. Control group: The control group will receive 10 mg of pethidine (Exir - Iran). Stop shivering. Timepoint: After surgery and the patient is discharged from anesthesia, shivering will be recorded within 15 minutes of treatment initiation and shivering time. Method of measurement: Observe and record the severity (shivering grade) and duration of shivering. Hemodynamic effects. Timepoint: After surgery and the patient is discharged from anesthesia, Patients with Grade 3 and 4 shivering, blood pressure and heart rate, oxygen saturation and axillary temperature will be measured every 5 minutes. Method of measurement: Blood pressure and heart rate measurement using a monitoring and oxygen saturation percentage using an pulseoximeter and axillary temperature using a digital thermometer. Tabriz University of Medical Sciences Approved 2019-07-03 Ethics committee of Tabriz University of Medical Sciences Tabriz University of Medical Sciences, Golgasht St., Tabriz Tabriz East Azarbaijan Iran (Islamic Republic of)