IRCT20141009019470N90 IRCT 2019-11-27 Shiraz University of Medical Sciences The Effect of Intraoperative Infusion of Dexmedetomidine on Acute and chronic postoperative pain after simple mastectomy The Effect of Intraoperative Infusion of Dexmedetomidine on Acute and chronic postoperative pain after simple mastectomy 2019-12-06 anticipated 110 Complete https://irct.ir/trial/41244 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Patients randomized block permutation through 55 were divided into two groups www.Randomization.com site, Blinding description: The volume of a 2 cc vial of dexmedetomidine is 200 mcg.   Therefore, 38 ml of distilled water is added to the dexmedetomidine vial. As a result, each 1 cc is equivalent to 5 mcg and is eventually infused at a dose of 0.4 mcg / kg. The placebo group received 40 ml of distilled water in the syringe as an infusion. The nurse responsible for completing the questionnaires and the nurse responsible for treating patients as well as patients in both groups were not aware of the assignment of patients to the groups. 2-3 Mastectomy. Intervention 1: Intervention group: Dexmedetomidine is injected to the patient at a dose of 0.4 mcg / kg. Intervention 2: Control group:40 ml distilled water is injected into the syringe as an infusion. No - There is not a plan to make this available Justification or reason for not sharing IPD is Its against our policy.