]>
IRCT20150706023084N3 IRCT 2019-10-11 Islamic Azad University Effect of vitamin c supplementation on procalcitonin biomarker in community acquired pneumonia Comparison of the effectiveness of vitamin c supplementation on procalcitonin biomarker in community acquired pneumonia 2018-03-06 anticipated 40 Complete https://irct.ir/trial/40807 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Randomization description: Simple randomization Random-number table, Blinding description: All patients who had the necessary conditions to enter the study were assigned randomly into two groups of drugs and placebo. Patients, researcher and doctors were unware of the medications or placebo interventions. Patients and medications were coded by someone who did not intervene in the study. 3 Community acquired pneumonia. Intervention 1: Intervention group: This group received one vitamin C 1000 mg EFF tab daily and other medications for treating pneumonia for 10 days. Serum procalcitonin was measured and checked at the beginning of patient's entrance and at the end of the study(after 10 days). Intervention 2: Control group: This group received one vitamin C placebo 1000 mg EFF tab daily and other medications for treating pneumonia for 10 days. Serum procalcitonin was measured and checked at the beginning of patient's entrance and at the end of the study(after 10 days). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There are no more informations
public Mahsa Nikzad
Sattarkhan stree, North habibollah street, North gholami street, No 5
Tehran Iran (Islamic Republic of) 1455773111 +98 21 6655 0318 mahsanikzad74@gmail.com Islamic Azad University scientific Mahsa Nikzad
Sattarkhan stree, North habibollah street, North gholami street, No 5
Tehran Iran (Islamic Republic of) 1455773111 +98 21 6655 0318 mahsanikzad74@gmail.com Islamic Azad University Iran (Islamic Republic of) Diagnosis of community acquired pneumonia by physician based on clinical symptoms, chest x-rey, patients's.history and lab test results Obtaining informed consent from the patients Patients older than 18 years old in both gender. 18 years 80 years Both Pregnancy or lactation Any hepatic or kidney failure Taking any chemothrapy medications and NSAIDs Taking antibiotics for other infectious disease at the same time Treatment - Drugs Placebo Intervention group: This group received one vitamin C 1000 mg EFF tab daily and other medications for treating pneumonia for 10 days. Serum procalcitonin was measured and checked at the beginning of patient's entrance and at the end of the study(after 10 days). Control group: This group received one vitamin C placebo 1000 mg EFF tab daily and other medications for treating pneumonia for 10 days. Serum procalcitonin was measured and checked at the beginning of patient's entrance and at the end of the study(after 10 days). Procalcitonin(PCT) is produced in c-cells of thyroid gland as a prohormone of calcitonin. PCT has emerged as promising marker for the diagnosis of infections, because higher level of pct is found in bacterial infections than in viral infections and non specific inflammatory disease. Serum is used for measure of level of procalcitonin. Timepoint: Serum level of procalcitonin was measured at the beginning and at the end of the study(after 10 days). Method of measurement: The serum pct level was measured by VIDAS Biomerieux and pct kit, prepared by ELFA. Student Approved 2018-03-03 Ethics committee of department of pharmaceutical tehran islamic azad university of medical science. Dr shariati street, Khaghani street, Tehran islamic azad university of medical science Tehran Tehran Iran (Islamic Republic of)