]>
IRCT20101130005280N28 IRCT 2019-07-14 Mashhad University of Medical Sciences Evaluation of the effect of FSH in treatment of oligoasthenospermia Evaluation of the response to treatment with FSH in patients with oligoasthenospermia with different levels of DFI 2019-07-23 anticipated 60 Complete https://irct.ir/trial/40456 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. 2 Oligoasthenospermia. Intervention group: Use of subcutaneous FSH in treatment of idiopathic oligoasthenospermia every other day for 6 months with dosage of 150 mg and comparison of Spermogram factors, hormone profile and sperm DNA damage before and after treatment. Yes - There is a plan to make this available What will be shared: All data can be shared after patients are made unidentifiable. When: Data can be accessible 6 months after results are published. To whom: Data will be available for researchers in universities and other scientific institutes. Conditions: Carrying out analysis on data is permitted. Where to obtain: Data can be accessible through sending an email to the corresponding author. How to obtain: After sending a request email to the corresponding author, data will be sent in 1 month. Comments:
public Mohsen Seyedi
Imam Reza Hospital, Imam Reza Square, Ebn_e_Sina Avenue
Mashhad Iran (Islamic Republic of) 9137913316 +98 51 3858 3885 seyediVM911@mums.ac.ir Mashhad University of Medical Sciences scientific Salman Soltani
Imam Reza Hospital, Imam Reza square, Ebn_e_sina Avenue
Mashhad Iran (Islamic Republic of) 9137913316 +98 51 3858 3885 SoltaniS@mums.ac.ir Mashhad University of Medical Sciences Iran (Islamic Republic of) Patient has an infertility problem Patient is not under any other treatment or does not have any indication of surgery oligoasthenospermia Patient does not have any background anatomical problems in urogenital system Patient's spouse is absolutely healthy in terms of fertility and has no problems 20 years 45 years Male Creation of any anatomical disorder like Varicocele in urogenital system during the research History of any previous medical intervention or previous surgery R86.9 Unspecified abnormal finding in specimens from male genital organs Treatment - Drugs Intervention group: Use of subcutaneous FSH in treatment of idiopathic oligoasthenospermia every other day for 6 months with dosage of 150 mg and comparison of Spermogram factors, hormone profile and sperm DNA damage before and after treatment Spermogram. Timepoint: before and after treatment (6 months after medication use). Method of measurement: Laboratory sampling. Test of DNA damage in sperm (DNA fragmentation index). Timepoint: before and after treatment (6 months after medication use). Method of measurement: Laboratory sampling. Mashhad University of Medical Sciences Approved 2019-04-16 Ethics Committee of Mashhad University of Medical Sciences Central Building of Mashhad University of Medical Sciences (Ghorshi),Daneshgah 16, Daneshgah Street Mashhad Razavi Khorasan Iran (Islamic Republic of)