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IRCT20180107038251N3 IRCT 2019-08-09 Arak University of Medical Sciences Effect of nebulized eucalyptus on ventilator associated pneumonia Effect of nebulized eucalyptus on ventilator associated pneumonia in ventilated patients 2014-07-23 anticipated 70 Complete https://irct.ir/trial/40418 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Other, Purpose: Prevention, Randomization description: Simple Randomization with Flip the coin method we used from this method for creating random sequence, that way we considered one of study groups as milk and other group as line and based on sample size we threw the coin and randomly assigned subjects to two groups, Blinding description: In this study, participants and evaluators of outcomes of the study are not aware of the allocation of groups. 3 Ventilator associated pneumonia. Intervention 1: Intervention group: Four ml of 5% eucalyptus are diluted in 10 ml normal saline and are nebulized in about 20 minutes through mechanical ventilator. This work is performed every 8 hours until extubation. Intervention 2: Control group: Ten ml normal saline are nebulized in about 20 minutes through mechanical ventilator. This work is performed every 8 hours until extubation. Yes - There is a plan to make this available What will be shared: Some of information about the main outcomes are shared after the article is published. When: After publishing article To whom: Researchers working in academic institute and industry professionals Conditions: To conduct further research in this field or use it in patients Where to obtain: nazaninamini69@yahoo.com How to obtain: After sending email Comments:
public Nazanin Amini
Arak University of Medical Sciences, Alamoll Huda Street, Railroad Street Arak Markazi Province
Arak Iran (Islamic Republic of) - +98 86 3313 6055 nazaninamini69@yahoo.com Arak University of Medical Sciences scientific Korosh Rezaei
Arak University of Medical Sciences, Alamoll Huda Street, Railroad Street Arak Markazi Province
Arak Iran (Islamic Republic of) - +98 86 3417 3524 k.rezaei@arakmu.ac.ir Arak University of Medical Sciences Iran (Islamic Republic of) 18-65 years old oral intubation Under ventilation for at least 3 days and up to 14 days lack of pulmonary infection, sepsis, pulmonary thromboembolism, atelectasis, Gastrointestinal inflammatory disease and severe hepatic disease. no allergy to herbal compounds 18 years 65 years Both nasal intubation J15.9 Unspecified bacterial pneumonia Prevention Placebo Intervention group: Four ml of 5% eucalyptus are diluted in 10 ml normal saline and are nebulized in about 20 minutes through mechanical ventilator. This work is performed every 8 hours until extubation Control group: Ten ml normal saline are nebulized in about 20 minutes through mechanical ventilator. This work is performed every 8 hours until extubation. Ventilator associated pneumonia. Timepoint: Ventilator associated pneumonia are measured on fifth, ninth day and before extubation. Method of measurement: Measurement of variables is based on Modified Clinical Pulmonary Infection Score (MCPIS) checklist. The instrument includes five criteria including temperature, white blood cell count, tracheal secretion , oxygenation, chest radiography, each score is 0 to 2, and total score is 10. If total score is equal to or greater than 6, pneumonia is detected. Arak University of Medical Sciences Approved 2014-07-14 Ethics committee of Arak University of Medical Sciences Arak University of Medical Sciences, Alamoll Huda Street, Railroad Street Arak Markazi Province Arak Markazi Iran (Islamic Republic of)