]>
IRCT20181006041252N12 IRCT 2019-06-18 Sabzevar University of Medical Sciences Comparison of the effect of Tamsulosin and Placebo on prevention of urinary retention after Herniorrhaphy, Varicocelectomy, and Anorectal Surgery. Comparison of the effect of Tamsulosin and Placebo on prevention of urinary retention after Herniorrhaphy, Varicocelectomy, and Anorectal Surgery. 2019-01-21 anticipated 150 Complete https://irct.ir/trial/39963 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization was conducted based on a permutation block by a statistical consultant using random allocation software and the output sequences A and B are available to the researcher, Accordingly, 6 blocks were allocated to patients, in each block, 2 from A treatment group, 2 from the B treatment group were placed. Eventually, after completing the blocks group A was treated with Group A is treated with Tamsulosin 0.4 mg and Group B is being treated with placebo. First, we determine all sixsome modes in which two individuals are assigned to group A and two to group B. Then we assign one of the digits 1 to 6 to each of the sixsome combinations (which includes thirty-six modes). In the next step, we must randomly select 6 blocks of six and write their combinations in succession. For this we have to make 6 samplings with replacement from a six-member community; 6 times, choose a random number between 1 and 6 and this process will continue until the end of the sampling and the difference between the two groups will not exceed a maximum of two (half the size of the block), Blinding description: Each person in the study will be assigned code A and B, that the researcher will only be known of the type of groups. Clinical care and participants are unaware of the groups. It should be noted that Tamsulosin and placebo are similar in appearance, color, and packaging. 3 Urinary retention. Intervention 1: Intervention group: Patients in this group receive 3 doses of Tamsulosin capsule 0.4 mg (2 doses prior to surgery 12 hours apart and one dose 6 hours after surgery) orally. Intervention 2: Control group: Patients in this group receive 3 doses of placebo capsules (2 doses prior to surgery, 12 hours apart and one dose 6 hours after surgery) orally. No - There is not a plan to make this available Justification or reason for not sharing IPD is No more information
public Dr. Hamidreza Baghani
Sabzevar University of Medical Sciences, Tohid Blvd., Sabzevar Town
Sabzevar Iran (Islamic Republic of) 9617913114 +98 51 4401 8378 Hamid.Baghani@yahoo.com Sabzevar University of Medical Sciences scientific Dr. Hamidreza Baghani
Sabzevar University of Medical Sciences, Tohid Blvd., Sabzevar Town
Sabzevar Iran (Islamic Republic of) 9617913114 +98 51 4401 8378 Hamid.baghani@yahoo.com Sabzevar University of Medical Sciences Iran (Islamic Republic of) Patients under the age of 50 years Patients undergoing urology or general surgery no limit 50 years Both Patients with the symptoms of urinary tract infection before surgery Patients with history of urinary retention Patients with a history of neurological disease Patients with a history of pelvic surgery Patients with a history of using Benzodiazepine, beta-agonist and alpha-agonist prior to surgery N20.9 Urinary calculus, unspecified Treatment - Drugs Treatment - Drugs Intervention group: Patients in this group receive 3 doses of Tamsulosin capsule 0.4 mg (2 doses prior to surgery 12 hours apart and one dose 6 hours after surgery) orally. Control group: Patients in this group receive 3 doses of placebo capsules (2 doses prior to surgery, 12 hours apart and one dose 6 hours after surgery) orally. Determine urinary retention. Timepoint: At the beginning of the study (before the intervention) and 24 hours after the intervention. Method of measurement: Measuring urine volume in 24 hours (less than 200 cc). Sabzevar University of Medical Sciences Approved 2016-06-20 Ethics committee of Sabzevar University of Medical Sciences Sabzevar University of Medical Sciences, Tohid Blvd, Sabzevar city Sabzevar Razavi Khorasan Iran (Islamic Republic of)