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IRCT20190514043591N1 IRCT 2019-08-28 Ferdowsi University of Mashhad The effectiveness of cognitive behavioral therapy based on exposure and response prevention on reduction of obsessive compulsive symptoms in scrupulosity and contamination obsessions The effectiveness of cognitive behavioral therapy based on exposure and response prevention on reduction of obsessive compulsive symptoms, changing P300 component and improving executive functioning in scrupulosity and contamination obsessions 2019-07-29 anticipated 75 Complete https://irct.ir/trial/39746 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization method is used to allocate individuals in groups, Blinding description: Participants were kept blind in this study. N/A Obsessive-compulsive disorder. Intervention 1: Intervention group 1: The group of scrupulosity patients under 10-15 sessions of exposure and response prevention. Intervention 2: Intervention group 2: The group of contamination patients under 10-15 sessions of exposure and response prevention. Intervention 3: Control group: They receive no intervention. Yes - There is a plan to make this available What will be shared: The total potential data can be shared after unidentifiable participant When: 6 months after publication To whom: people working in academic institutions Conditions: Confidential raw data for secondary analysis will be available to researchers. Where to obtain: farzad farhoodi 00989133590446 How to obtain: Submit a proposal from prestigious academic institution Comments:
public Hamid Mirhoseini
Central Building of Yazd University of Medical Sciences, Bahonar Square, Yazd
Yazd Iran (Islamic Republic of) 9177948994 +98 51 3880 5000 miehoseini.h@gmail.com Yazd University of Medical Sciences scientific Javad Salehi Fadardi
Azadi Square, Mashhad, Razavi Khorasan Province, Iran
Mashad Iran (Islamic Republic of) 9177948974 +98 51 3880 2415 jsfadardi@gmail.com Ferdowsi University of Mahhad Iran (Islamic Republic of) ِDiagnosis of obsessive-compulsive disorder through a structured clinical interview based on DSM-IV criteria The minimum score for the diagnosis of obsessive-compulsive disorder in the Yale-Brown Compulsive Scale The minimum score for the diagnosis of obsessive-compulsive disorder in the Penn's Religious Observatory. Aged 18 to 55 years The minimum cycle level of education 18 years 55 years Both The risk of psychiatric disorder such as anxiety disorders, major depressive disorder, bipolar disorder, significant neurological disorder such as epilepsy, History of severe head injury Impaired vision and hearing Personality disorder Consumption of the drug or the simultaneous consumption of the drug in the last two years F42 Obsessive-compulsive disorder Treatment - Other Treatment - Other N/A Intervention group 1: The group of scrupulosity patients under 10-15 sessions of exposure and response prevention. Intervention group 2: The group of contamination patients under 10-15 sessions of exposure and response prevention. Control group: They receive no intervention. Obsessive compulsive symptoms. Timepoint: Before the intervention, After intervention. Method of measurement: Yale-Brown's Obsessive-Compulsive Scale Religious Penny Questionnaire. Executive functioning. Timepoint: Before the intervention, After intervention. Method of measurement: Wisconsin Card Sorting Test. P300 component. Timepoint: Before the intervention, After intervention. Method of measurement: ERP. Depression. Timepoint: Before the intervention, After intervention. Method of measurement: Beck scale. Ferdowsi University of Mashhad Approved 2019-07-29 Ethics committee of Ferdowsi University of Mashhad Azadi Square, Mashhad, Razavi Khorasan Province, Iran Mashhad Razavi Khorasan Iran (Islamic Republic of)