IRCT20160815029369N2 IRCT 2019-07-27 Tehran University of Medical Sciences Evaluation of blood components on healing of extracted teeth site Radiographic and histologic comparison of changes in dental sockets grafted with LPRF and sockets without intervention a randomized controlled clinical tiral study 2019-06-05 anticipated 26 Complete https://irct.ir/trial/39721 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: with regard to simple randomization method we make 2 groups consist of test and control then we wrote them on 26 rolled paper and put them in a basket. each patient take a paper from basket and so her/his group will appear, Blinding description: The persons who analyse the radiographic image and histologic biopsy do not know about each sample group(test or control). N/A ridge preservation. Intervention 1: Intervention group: the teeth will have been extracted atraumatically with Periotome. four 10 ml tubes of blood will have been taken from patients and Leukocyte platelet fibrin will have been prepare with 2700 rpm 12 minutes protocol(Intraspine. Intralock .florida. USA). LPRF clots inserted in site of extraction and gently packed.we suture the entrance of socket with 5.0 nylon with mattress suture.we prescribe Iboprofen 400mg tid for 2 days and Cholorhexidine mouth rinse bid for one week. after one week the suture will have been removed. CBCT radiography will have been taken immediately after and 8 weeks later. in day of implant placement the histologic biopsy will have been obtained from site of implant placement using Trephine bur as a initial drill. Intervention 2: Intervention group: the teeth will be extracted atraumatically with Periotome. we suture the entrance of socket with 5.0 nylon with mattress suture.we prescribe Iboprofen 400mg tid for 2 days and Cholorhexidine mouth rinse bid for one week.after one week the suture will have been removed. CBCT radiography will have been taken immediately after and 8 weeks later. in day of implant placement the histologic biopsy will have been obtained from site of implant placement using Trephine bur as a initial drill. No - There is not a plan to make this available Justification or reason for not sharing IPD is there is no more information available.