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IRCT138902113846N1 IRCT 2014-06-07 Shiraz University of Medical Sciences Intravitreal bevacizumab(Avastin) for macular edema secondary to uveitis: 1 year results of a prospective pilot study CME : cystoid macular edema Intravitreal bevacizumab(Avastin) for macular edema secondary to uveitis: 1 year results of a prospective pilot study 2013-08-23 anticipated 30 Complete https://irct.ir/trial/3972 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. N/A Macular edema secondary to uveitis. intra vitreal injection of bevacizomab(avastin).
public Dr. Hooman Razmi
Department of ophthalmology, Khalili hospital, Khalili Avenue
Shiraz Iran (Islamic Republic of) +98 71 1627 1382 hooman2482@gmail.com Shiraz University of Medical Sciences scientific Dr. Mansour Rahimi
Department of ophthalmology, Khalili hospital, Khalili Avenue
Shiraz Iran (Islamic Republic of) +98 71 1627 1382 mrahimi@sums.ac.ir Shiraz University of Medical Sciences Iran (Islamic Republic of) In a prospective clinical trial consecutive 30 patients with uveitis and CME will be enroll in the study. None of the patients will have a systemic or an ocular disease other than the one causing uveitis. Patients with history of other diseases causing macular edema (such as diabetes mellitus and retinal vein occlusions) will be excluded from the study. All of the patients should have decreased vision due to Cystoid Macular Edema (CME), no limit no limit Both H35.8 Other specified retinal disorders Treatment - Surgery intra vitreal injection of bevacizomab(avastin) Best corrected visual acuity. Timepoint: Before injection and 1, 3, 6 and 12 months after injection. Method of measurement: Standard snelen chart and log mar. Central macular thickness. Timepoint: Before injection and 1, 3, 6 and 12 months after injection. Method of measurement: SD-OCT. Complication of intravitreal injection of bevacizumab. Timepoint: During 1 year after injection. Method of measurement: Routine physical examination. Shiraz University of Medical Sciences Approved 2013-11-20 Ethics Committee of Shiraz University of Medical Sciences Shiraz University of Medical Sciences , Zand Street Shiraz Iran (Islamic Republic of)