IRCT20190518043622N1 IRCT 2020-09-04 Shiraz University of Medical Sciences Evaluation of Bevacizumab effect on diabetic macular edema in diabetic patients . Evaluation of the changes in the OCT angiography after the Intra Vitreal Injection of Bevacizumab in diabetic Patients with Clinically Significant Macular Edema. 2018-06-04 anticipated 35 Complete https://irct.ir/trial/39697 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Diagnostic, Other design features: In this study, we assessed features of OCT Angiography images to find vascular and morphological changes before and after the injection of Bevacizumab. 2 Diabetic macular edema. Intervention group: ِIntravitreal injection of 1.25 mg of Bevacizumab(or stivant) will be performed by other expert in operation room under sterile condition ( for patients with diabetic macular edema). The patients will be followed before and one month after operation. In this study we did not intervene and we analyzed the OCTA images before and after what other experts injected to evaluate macular changes.. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Coordination with other beneficiaries