]>
IRCT20160118026097N6 IRCT 2021-05-11 Gorgan University of Medical Sciences Comparison of low dose and high dose of furazolidone in the treatment of Helicobacter pylori infection ندارد Comparison of low dose and high dose of furazolidone in the treatment of Helicobacter pylori infection 2015-07-23 anticipated 170 Complete https://irct.ir/trial/39664 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Health service research, Randomization description: This study will be performed by a random sampling method, block allocation. In such a way that In this study, 60 patients with corona will be randomly divided into two groups. The selection of groups will be based on the fact that individuals will be assigned to groups based on block randomization. Block size 4 is considered. So we have six blocks of four, ABAB, ABBA, AABB, BAAB BBAA, BABA. The selection of each block will also be random and will be done using dice. For example, if the number 5 comes in the dice roll, the AABB block is considered and Therefore, the first two patients are assigned to treatment A, and the two patients are then assigned to treatment B.The dice will be thrown ten times to complete the allocation of patients to treatment groups. Treatment with dexamethasone and control will also be based on accident (coin toss). 3 Helicobacterpylori Eradication. Intervention 1: Intervention group 1: After obtaining informed consent and full explanation of the treatment process to the patient and his companions regarding the treatment process, under low-dose four-drug treatment (OfAB) including amoxicillin mg-BD 1000, furazolidone mg-BD 100, omeprazole mg-BD20, and bismuth 240 mg-BD subcitrate for 2 weeks. Intervention 2: Intervention group 2: After obtaining informed consent and full explanation of the treatment process to the patient and his companions about the treatment process, under treatment with four high-dose drugs (OFAB) including: amoxicillin mg-BD 1000, furazolidone mg-BD 200, omeprazole mg-BD20 and bismuth sub-citrate 240 mg-BD for 2 weeks. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is The final report is not completed.
public jamshid vafaeemanesh
Qom - Shahid Lavasani Street (Coastal) - Qom University of Medical Sciences
qom Iran (Islamic Republic of) 3713649373 +98 25 3612 2526 jvafaeemanesh@gmail.com Ghoum University of Medical Sciences scientific jamshid vafaeemanesh
Qom - Shahid Lavasani Street (Coastal) - Qom University of Medical Sciences
qom Iran (Islamic Republic of) 3713649373 +98 25 3612 2526 jvafaeemanesh@gmail.com Ghoum University of Medical Sciences Iran (Islamic Republic of) Peptic ulcer diagnosis with endoscopic diagnosis test Helicobacter pylori infection with RUT consent to cooperate 18 years 100 years Both Pregnancy Cancer or Liver Failure Diabetes Mellitus History of Cigarette History of Alcohol History of Drug Sensitivity K25 Gastric ulcer Treatment - Drugs Treatment - Drugs Intervention group 1: After obtaining informed consent and full explanation of the treatment process to the patient and his companions regarding the treatment process, under low-dose four-drug treatment (OfAB) including amoxicillin mg-BD 1000, furazolidone mg-BD 100, omeprazole mg-BD20, and bismuth 240 mg-BD subcitrate for 2 weeks. Intervention group 2: After obtaining informed consent and full explanation of the treatment process to the patient and his companions about the treatment process, under treatment with four high-dose drugs (OFAB) including: amoxicillin mg-BD 1000, furazolidone mg-BD 200, omeprazole mg-BD20 and bismuth sub-citrate 240 mg-BD for 2 weeks. Response to treatment-Helicobacter pylori eradication after drug treatment with urease respiratory test. Timepoint: Six weeks after drug treatment. Method of measurement: Urease Respiratory Test. Gorgan University of Medical Sciences Approved 2015-06-22 Golestan University of Medical Sciences Golestan Research Center of Gastroenterology and Hepatology-GRCGH (GOUMS), Golestan University of Medical Sciences, Gorgan, Iran gorgan Golestan Iran (Islamic Republic of)