IRCT20150822023705N12 IRCT 2019-09-03 Kermanshah University of Medical Sciences Compareing effects of Trimipramine and Placebo on temptation and rate of relapse The efficacy of Trimipramine in reducing the temptation and rate of relapse of methamphetamine use compared with placebo (clinical trial with a control group) 2019-07-06 anticipated 132 Complete https://irct.ir/trial/39617 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients are divided into two equal groups (A and B) based on a randomized six-block table designed using Random allocation software. In order to randomly assign 132 patients to the intervention and control groups, six different blocks of 22 different letters A and B, which indicate the terminals of the trimimipermin and placebo groups, are initially created. These blocks are then numbered from one to six. In the next step, each of these blocks is randomly selected by performing 6 drawings from numbers 1 to 6 each. Thus, in each lottery, by selecting a block, a combination of 22 letters of the letters A (trimimipermin group) and B (placebo group) is obtained. At the end of the 6 drawings, after selecting 6 blocks, a total of 132 The letters A and B will be obtained. The resulting combination of letters A and B is single, and are placed in 132 separate and sealed envelopes, respectively. following each patient recourse an envelope is opened to determine the group of that patient, Blinding description: The medication and placebo are delivered to the patient without sticking the label. The doctor is also unaware of the type of drug used in each group. The color and smell of main drug and placebo are the same. 2 Methamphetamine dependency. Intervention 1: Intervention group: The group will receive Trimipramine treatment in two months. The daily dose will be two pills that the person will receive 75 mg in the first month and 150 mg in the second month. These pills will be given to patients without knowledge of the patient and the examiner, and the code for each drug will be recorded in the patient's questionnaire. Trimipramine will be purchased from Tehran Chemistry Pharmaceutical Company. Intervention 2: Control group: The control group will receive placebo treatment in two months. Daily drug intake will be two pills. Placebo pills (lactose powder, gelatin solution, 5% and Vocel) in terms of shape, size, color and smell are similar to the Trimipramine pills. The placebo will be provided by the Kermanshah Pharmaceutical Faculty. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is اطلاعات بیشتری وجود ندارد