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IRCT20150119020715N10 IRCT 2019-06-16 Arak University of Medical Sciences Effect of oral livergol on liver enzymes in patients with Leukemia Evaluation of the effect of oral livergol on liver enzymes in patients with Leukemia in the Preservative Phase 2019-06-21 anticipated 40 Complete https://irct.ir/trial/39567 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: A simple randomization is done with sealed envelope tools in such a way that the letters A and B are inserted in the envelopes and patients are asked to select an envelope that the intervention group A and the group B they will be tested, Blinding description: This means that patients in groups do not know the used drugs, and drugs has similar packaging, two drugs are similar in color, two drugs are similar in taste and odor. 3 Leukemia in the Preservative Phase. Intervention 1: Intervention group: In cases under 12 years of age take 70 mg and over 12 years of age take 140 mg of Liverghol oral pills two times per day, for 6 months. Intervention 2: Control group: The same placebo take two times per day, for 6 months. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information
public Aziz Eghbali
Amir-Kabir Hospital, Basij Square, Arak, Iran
Arak Iran (Islamic Republic of) 3819693345 +33 135075 dr.eghbali@arakmu.ac.ir Arak University of Medical Sciences scientific Aziz Eghbali
Amir-Kabir Hospital, Basij Square, Arak, Iran
Arak Iran (Islamic Republic of) 3819693345 +33 135075 dr.eghbali@arakmu.ac.ir Arak University of Medical Sciences Iran (Islamic Republic of) Patients over 5 years of age with leukemia in the preservative phase referring to Amir Kabir hospital in Arak Informed consent of the participants in the study Disrupted liver enzymes (AST and ALT greater than 60). Total cholesterol above 200 Total bilirubin equal to or greater than 2 GGT more than 60 3 years no limit Both With other blood diseases and liver diseases such as HBV, HCV and HIV C95.9 Leukemia, unspecified Treatment - Drugs Placebo Intervention group: In cases under 12 years of age take 70 mg and over 12 years of age take 140 mg of Liverghol oral pills two times per day, for 6 months. Control group: The same placebo take two times per day, for 6 months. Liver Enzymes. Timepoint: Before treatment, with a month's interval in six month from starting treatment. Method of measurement: Blood tests. Arak University of Medical Sciences Approved 2019-01-21 Ethics committee of Arak University of Medical Sciences Sardasht Arak Markazi Iran (Islamic Republic of)