IRCT20080901001165N42 IRCT 2019-11-30 Tabib daru pharmaceutical company Effect of Aloe vera capsule in control of gastroesophageal reflux disease To evaluate the efficacy and safty of Aloe vera capsule in gastroesophageal reflux disease patients and comparing the control of symptoms with pantoprazole 2019-12-21 anticipated 120 Complete https://irct.ir/trial/39469 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Accidental assignment to intervention and control groups using a random number table, Blinding description: The patient groups are divided into three groups, and every one Including researcher, health care personnel (doctors, nurses, pharmacists), participating patients involved in the study are not known to have any type of control or intervention. All patients are aware of the study. 3 gastroesophageal reflux disease. Intervention 1: Intervention group: Aloe Vera capsule for 28 day, twice a day and pantoprazole for 28 day, once a day. Intervention 2: Control group: pantoprazole for 28 day, once a day. Intervention 3: Intervention group: placebo capsule for 28 days, twice daily and pentoprazole for 28 days, once daily. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no more information