IRCT20121021011192N9 IRCT 2019-12-03 Shahid Beheshti University of Medical Sciences The effect of melatonin in Ulcerative colitis Evaluation of the effect of melatonin on clinical, biochemical parameters and quality of life in Ulcerative colitis patients 2019-05-22 anticipated 40 Complete https://irct.ir/trial/39185 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple individual randomization with Microsoft Excel software, Blinding description: Participants, principle investigator, healthcare providers (Physicians, nurses) who care for participants during the trial, data collectors and outcome assessors all are blinded by providing placebo melatonin in same size, shape color, odor and package with real melatonin tablet which organized just by one responsible co-researcher has no involvement in running study. 3 Ulcerative colitis. Intervention 1: Intervention group: Addition of melatonin tablet orally 3 mg/d to UC regimen for 3 months. Intervention 2: Control group: Addition of melatonin placebo tablet orally 3 mg/d to UC regimen for 3 months. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information.