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IRCT20190422043344N1 IRCT 2019-06-17 Bojnourd University of Medical Sciences " Effect of Glycyrrhiza glabra extract on salivary volume" Evaluation of the effect of Glycyrrhiza glabra extract in the form of D-Reglis herbal pills on amount of human Saliva: A Crossover randomized clinical trial study 2019-03-05 anticipated 20 Complete https://irct.ir/trial/39084 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Crossover, Purpose: Treatment, Randomization description: The subjects were divided into two groups A and B according to a randomized double blind block design, Blinding description: In this double-blind study, participants, researchers are unaware of prescription drugs. 3 . Intervention 1: Intervention group: A single dose of 380 milligrams of licorice extract produced by Iran Daruk Co., with 200 cc was prescribed.To prevent the bias between the drug and the placebo, they are placed in the same capsules. Intervention 2: Control group: Placebo (starch), in capsules of the same size and shape as capsules of the drug, and with 200 cc of water was prescribed. Yes - There is a plan to make this available What will be shared: Information about the main consequence, have the ability to share, after unidentifiable people. When: Start the access period 6 months after printing the results To whom: Researchers working in academic & scientific institutions Conditions: The use of data in order to complete scientific information and research is permissible and sending a request for access to data has not a specific condition. Where to obtain: 1.North Khorasan University of Medical Sciences, dental College 2. s.etemadzade@gmail.com How to obtain: After sending the email, it will be answered for a few days Comments:
public Mehdi Mohammad Sadeghian
Shahriar St., North Khorasan University of Medical Sciences
Bojnourd Iran (Islamic Republic of) 9417694735 +98 58 3226 1272 dr.mm.sadeghian@gmail.com Bojnourd University of Medical Sciences scientific Mehdi Mohammad Sadeghian
Shahriar St., North Khorasan University of Medical Sciences
Bojnourd Iran (Islamic Republic of) 9417694735 +98 58 3624 5629 dr.mm.sadeghian@gmail.com Bojnourd University of Medical Sciences Iran (Islamic Republic of) Healthy volunteers who have no history of dry mouth aged 18-35 years Signature of informed consent form 18 years 35 years Both 1- Pregnancy 2. Those who suffer from dry mouth and take medication 3. Sensitivity to licorice 4- Use of cigarettes 5- Drug use in the previous month before the study Treatment - Drugs Placebo Intervention group: A single dose of 380 milligrams of licorice extract produced by Iran Daruk Co., with 200 cc was prescribed.To prevent the bias between the drug and the placebo, they are placed in the same capsules. Control group: Placebo (starch), in capsules of the same size and shape as capsules of the drug, and with 200 cc of water was prescribed. The weight of saliva secreted from all salivary glands in the mouth. Timepoint: Measurement of saliva volume at the beginning of the study and at 20, 40, 60, 90, 120, and 180 minutes after the administration of the D-REGLIS tablet and placebo. Method of measurement: digital Balance. Bojnourd University of Medical Sciences Approved 2019-03-05 National commitee of North khorasan University of medical sciences Shahriar Ave., North khorasan University of Medical Sciences Bojnourd North Khorasan Iran (Islamic Republic of)