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IRCT20121223011856N2 IRCT 2019-04-25 Esfahan University of Medical Sciences Effect of Chlorhexidine on postextrction pain Effectiveness of preoperative chlorhexidine mouthwash on pain after lower posterior teeth removal : A Randomized, Double blind Clinical Trial 2019-04-21 anticipated 170 Complete https://irct.ir/trial/38851 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Patients will be randomly allocated to a treatment group based on the flip of a coin, Blinding description: 0.5 to 1 h before performing extractions, subjects will be given a dark bottle containing 15 ml of either chlorhexidine 0.2% or placebo but they have no idea of the type of the solution. we will ask the clinician to perform extractions in equal situation for all patients while he has no information about the two groups. 3 postoperative pain after tooth extraction. Intervention 1: Intervention group: 0.5 to 1 hours before performing extractions patient in intervention group will be given a dark bottle containing 15 ml of 0.2% chlorhexidine gluconate mouthwash (BEHSA). they will rinse the solution around their mouth for two minutes. the extractions will be done by an expert clinician. After performing extractions, patients will receive 10 pills of Acetaminophen 325 (EXIR) to be taken in case of excessive pain. patient analgesic intake and postoperative pain will be recorded by 4 telephone interviews 6, 12, 24 and 48 postoperative hours. Subjects will be asked to make VAS evaluation of their pain. Likewise subjects will be asked if they have used any prescribed analgesics and if so, the dosage will be asked. Intervention 2: Control group: 0.5 to 1 hours before performing extractions patient in control group will be given a dark bottle containing 15 ml of placebo mouthwash (one liter of placebo contains 1 liter of sterile normal saline (Samen company) plus one drop of natural edible colours made by colour splash company) . they will rinse the solution around their mouth for two minutes. the extractions will be done by an expert clinician. After performing extractions, patients will receive 10 pills of Acetaminophen 325 (EXIR) to be taken in case of excessive pain. patient analgesic intake and postoperative pain will be recorded by 4 telephone interviews 6, 12, 24 and 48 postoperative hours. Subjects will be asked to make VAS evaluation of their pain. Likewise subjects will be asked if they have used any prescribed analgesics and if so, the dosage will be asked. No - There is not a plan to make this available Justification or reason for not sharing IPD is "There is no further information"
public Abbas Haghaighat
Hezargarib st
isfahan Iran (Islamic Republic of) 81746-73461 +98 21 8871 4273 haghighat@dnt.mui.ac.ir Esfahan University of Medical Sciences scientific Abbas Haghighat
hezarjarib st
isfahan Iran (Islamic Republic of) 81746-73461 +98 219025795 haghighat@dnt.mui.ac.ir Esfahan University of Medical Sciences Iran (Islamic Republic of) patients will be between 18 and 80 years old. patients be healthy and not on any regular medication. patients will not have any of pain inducing conditions such as an aching tooth at the time of the surgery. 18 years 80 years Both patients will be excluded if they ingested any medications including oral contraceptives, analgesics and antibiotics as of 5 days prior to the operation. smokers will be excluded Prevention Prevention Intervention group: 0.5 to 1 hours before performing extractions patient in intervention group will be given a dark bottle containing 15 ml of 0.2% chlorhexidine gluconate mouthwash (BEHSA). they will rinse the solution around their mouth for two minutes. the extractions will be done by an expert clinician. After performing extractions, patients will receive 10 pills of Acetaminophen 325 (EXIR) to be taken in case of excessive pain. patient analgesic intake and postoperative pain will be recorded by 4 telephone interviews 6, 12, 24 and 48 postoperative hours. Subjects will be asked to make VAS evaluation of their pain. Likewise subjects will be asked if they have used any prescribed analgesics and if so, the dosage will be asked. Control group: 0.5 to 1 hours before performing extractions patient in control group will be given a dark bottle containing 15 ml of placebo mouthwash (one liter of placebo contains 1 liter of sterile normal saline (Samen company) plus one drop of natural edible colours made by colour splash company) . they will rinse the solution around their mouth for two minutes. the extractions will be done by an expert clinician. After performing extractions, patients will receive 10 pills of Acetaminophen 325 (EXIR) to be taken in case of excessive pain. patient analgesic intake and postoperative pain will be recorded by 4 telephone interviews 6, 12, 24 and 48 postoperative hours. Subjects will be asked to make VAS evaluation of their pain. Likewise subjects will be asked if they have used any prescribed analgesics and if so, the dosage will be asked. Patients pain. Timepoint: 6,12,24 and 48 hours after extractio. Method of measurement: patients pain will be assessed using a VAS (Visual Analog Scale) and the number of analgesic used. Esfahan University of Medical Sciences Approved 2018-12-29 Ethics committee of Isfahan University of Medical science Hezarjarib st Isfahan Isfehan Iran (Islamic Republic of)