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IRCT201604273742N4 IRCT 2016-09-09 Vice chancellor for research, Tabriz University of Medical Sciences. Sertraline effect on hypotension during hemodialysis Sertraline effect on hypotension during hemodialysis 2016-05-21 anticipated 30 Complete https://irct.ir/trial/3855 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. N/A Hemodialysis. This study will be done in a single group, due to low number of available patients. Systolic blood pressure, diastolic blood pressure, heart rate, and mean arterial pressure of patients will record before intervention during hemodialysis. Patients will receive 50 mg sertraline daily for two weeks. Systolic blood pressure, diastolic blood pressure, heart rate, and mean arterial pressure of patients will record again during hemodialysis..
public Dr Hamid Noshad
Faculty of Medicine, Tabriz University of Medical Sciences, Daneshgah Street, Tabriz.
Tabriz Iran (Islamic Republic of) +98 41 3541 5023 medicalresearchtbz@gmail.com Tabriz University of Medical Sciences. scientific Dr Hamid Noshad
Faculty of Medicine, Tabriz University of Medical Sciences, Daneshgah Street, Tabriz.
Tabriz Iran (Islamic Republic of) +98 41 3541 5023 medicalresearchtbz@gmail.com Tabriz University of Medical Sciences. Iran (Islamic Republic of) Inclusion criteria: age between 18 to 75 years old; resistant hypotension during hemodialysis; no specific reason for resistant hypotension; informed consent to participate in the study. Exclusion criteria: use of any selective serotonin reuptake inhibitors. 18 years 75 years Both Z99.2 Dependence on renal dialysis Treatment - Drugs This study will be done in a single group, due to low number of available patients. Systolic blood pressure, diastolic blood pressure, heart rate, and mean arterial pressure of patients will record before intervention during hemodialysis. Patients will receive 50 mg sertraline daily for two weeks. Systolic blood pressure, diastolic blood pressure, heart rate, and mean arterial pressure of patients will record again during hemodialysis. Systolic blood pressure. Timepoint: Beginning of study, two weeks later. Method of measurement: Measuring blood pressure. Diastolic blood pressure. Timepoint: Beginning of study, two weeks later. Method of measurement: Measuring blood pressure. Heart rate. Timepoint: Beginning of study, two weeks later. Method of measurement: clinical examination. Mean arterial pressure. Timepoint: Beginning of study, two weeks later. Method of measurement: Measuring blood pressure. Adverse effects. Timepoint: Two weeks later. Method of measurement: Patient follow up. Vice chancellor for research, Tabriz University of Medical Sciences. Approved 2015-11-23 Tabriz University of Medical Sciences. Tabriz University of Medical Sciences, Daneshgah Street, Tabriz, Eastern Azerbaijan, Iran. Tabriz Iran (Islamic Republic of)