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IRCT20190317043082N1 IRCT 2019-04-05 Iran University of Medical Sciences Effect of oxygen therapy in preventing contrast nephropathy The study of oxygen therapy in preventing contrast nephropathy in patients with acute coronary syndrome undergoing emergent angiography refereed to Resoul Akram hospital in 2018 2018-08-12 anticipated 204 Complete https://irct.ir/trial/38486 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The random number table and block randomization method were used using http://www.randomizer.org. In this method, eligible patients are divided into blocks of 4 patients. We created random numbers using computer. Based on the determined numerical range to enter individuals in each group, half of the patients in each block assigned to supplementary oxygen and half of them in other group . 3 Coronary artery disease. Intervention 1: Intervention group: : This group received 2 to 3 liters of oxygen per minute from the 10 minutes before the start of the procedure until the end of the procedure. ABG were taken prior to receiving oxygen and at the end of the procedure. The dose of the contrast agent was at least 100 ml and maximum 200 ml. Serum creatinine level was checked for all patients before and 48 hours after the procedure. Intervention 2: Control group: This group did not receive supplementary oxygen. This group inhaled the oxygen in the room air. ABG were taken prior to receiving oxygen and at the end of the procedure. The dose of the contrast agent was at least 100 ml and maximum 200 ml. Serum creatinine level was checked for all patients before and 48 hours after the procedure. Yes - There is a plan to make this available What will be shared: All potential data is shareable after being unidentifiable When: Up to 2019-09-01 To whom: All university researchers Conditions: Email Where to obtain: Email How to obtain: Eamil Comments:
public Tahereh Zarouk Ahi Mahalleh
Number 21, Dameshgh St., Vali-e Asr Ave., Tehran
Tehran Iran (Islamic Republic of) 1449614535 +98 21 8889 6692 zarouk.t@iums.ac.ir Tehran University of Medical Sciences scientific Tahereh Zarouk Ahi Mahalleh
Number 21, Dameshgh St., Vali-e Asr Ave., Tehran
Tehran Iran (Islamic Republic of) 1449614535 +98 21 8889 6692 zarouk.t@iums.ac.ir Tehran University of Medical Sciences Iran (Islamic Republic of) Male or female patients over 35 years old Suspected of coronary artery disease 35 years no limit Both Arterial oxygen saturation less than 90% Having end stage renal disease Patients undergoing dialysis coronary artery bypass surgery Candidate for emergency coronary artery bypass surgery I24.9 Acute ischemic heart disease, unspecified Treatment - Drugs Treatment - Drugs Intervention group: : This group received 2 to 3 liters of oxygen per minute from the 10 minutes before the start of the procedure until the end of the procedure. ABG were taken prior to receiving oxygen and at the end of the procedure. The dose of the contrast agent was at least 100 ml and maximum 200 ml. Serum creatinine level was checked for all patients before and 48 hours after the procedure. Control group: This group did not receive supplementary oxygen. This group inhaled the oxygen in the room air. ABG were taken prior to receiving oxygen and at the end of the procedure. The dose of the contrast agent was at least 100 ml and maximum 200 ml. Serum creatinine level was checked for all patients before and 48 hours after the procedure. Serum creatinine level. Timepoint: Before the procedure and 48 hours later. Method of measurement: Blood sampling. Iran University of Medical Sciences Approved 2016-07-22 Ethics committee of Iran University of Medical Sciences Hazrate Rasoole Akram Hospital,Niayesh St,Satarkhan Av, Tehran Tehran Tehran Iran (Islamic Republic of)