<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20190316043067N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2019-04-23</date_registration>
      <primary_sponsor>Shahid Beheshti University of Medical Sciences</primary_sponsor>
      <public_title>Effect of wrist mobilization techniques on grip strength and force sense</public_title>
      <acronym></acronym>
      <scientific_title>Study of immediate effects of Mulligan and Maitland mobilization techniques on grip strength and grip force sense in healthy young women</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2019-04-30</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>91</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/38351</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Other design features: This study also investigates the relationship between joint mobilization and force sense, Randomization description: Tossing a coin. Participants were allocated in one of the two groups according to what the coin indicated.
 Simple randomization, Blinding description: Participants are not informed which mobilization technique is applied.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Comparison of the effects of Maitland and Mulligan mobilization techniques on hand power. Grip strength was measured in both groups before and after applying the mobilization of the wrist using the Maitland and Mulligan techniques..</hc_freetext>
      <i_freetext>Intervention 1: Intervention group one: Maitland mobilization grade III with a frequency of 1 Hz is applied on the subject’s wrist to promote wrist extension. In grade III of Maitland mobilization technique, a large amplitude of oscillating mobilizing movements are applied rhythmically to the barrier of the range of movement.  Application of the Maitland mobilization technique takes 3 minutes. In this technique, the subject is in the supine position and her forearm is placed in mid position. The physiotherapist is standing in front of the subject and grasps the radio-carpal joint of the dominant hand. Therapist’s both thumbs are placed on the dorsal side of the proximal carpal row just distal to the radial and ulnar styloid processes. Thumb and index fingers hold the scaphoid, lunate and partially triquetrum. Other fingers are placed on the palmar side of carpal bones. Before beginning the mobilization in palmar direction, joint slack is taken. Index fingers and thumbs are the major contact points which apply the force. Extension movement is applied through local grip with simultaneous wrist extension. Oscillation is finished while forearm turns back to primary position(12). Intervention 2: Intervention group: The technique was done in 3 sets of 6 movements and lasted about 2/5 minutes. The Mulligan technique includes carpal lateral glide with non-weight bearing wrist flexion/extension. The subject is in sitting position with the elbow in 90˚ flexion, the forearm in mid pronation, the wrist in resting position and the hand in neutral position. The therapist is in front of the subject and fixes the distal end of the radius laterally with the first web space. The therapist’s other hand grasped the medial side of the subject’s wrist joint. Then through the first web space a lateral glide was applied to the proximal carps. While the therapist was maintaining the lateral glide, the subject was asked to flex and extend her wrist and apply the pressure at the end of movement in favor of wrist extension. If required, slight adjustments were made to the intensity and direction of the lateral glide.    Because the wrist joint was small, the mobilization was done slowly.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Undecided - It is not yet known if there will be a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for indecision in sharing IPD is no more information</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Seyedeh Forough Abtahi nezhad moghadam</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>1616913111, Damavand Ave, Imam Hossein SQ, School of Rehabilitation, Tehran, Iran.</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>1616913111</zip>
        <telephone>+98 21 7754 2057</telephone>
        <email>f.abt70@yahoo.com</email>
        <affiliation>Shahid Beheshti University of Medical Sciences</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Seyedmajid Hosseini</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Damavand Ave, Imam Hosseini SQ, Postal code: 1616913111</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>1616913111</zip>
        <telephone>+98 21 7754 2057</telephone>
        <email>majid_hoseini@sbmu.ac.ir</email>
        <affiliation>Shahid Beheshti University of Medical Sciences</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>females (age 18- 30 years) with normal BMI between 20-25
Participant states that she is healthy and has no problem (asymptomatic).</inclusion_criteria>
      <agemin>18 years</agemin>
      <agemax>30 years</agemax>
      <gender>Female</gender>
      <exclusion_criteria>Being athletes (Exercise at least three days a week for two hours)
their job is dependent on heavy manual tasks
history of carpal tunnel syndrome  in the previous 6 months
history of wrist tendonitis  in the previous 6 months
history of hand fracture and immobilization for wrist or hand in the previous 6 months
receiving manual techniques such as joint mobilization, massage, muscle energy technique and manipulation in the previous 6 months
participants who are not willing to continue the study</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code></hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword></hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Rehabilitation</i_code>
      <i_code>Rehabilitation</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group one: Maitland mobilization grade III with a frequency of 1 Hz is applied on the subject’s wrist to promote wrist extension. In grade III of Maitland mobilization technique, a large amplitude of oscillating mobilizing movements are applied rhythmically to the barrier of the range of movement.  Application of the Maitland mobilization technique takes 3 minutes. In this technique, the subject is in the supine position and her forearm is placed in mid position. The physiotherapist is standing in front of the subject and grasps the radio-carpal joint of the dominant hand. Therapist’s both thumbs are placed on the dorsal side of the proximal carpal row just distal to the radial and ulnar styloid processes. Thumb and index fingers hold the scaphoid, lunate and partially triquetrum. Other fingers are placed on the palmar side of carpal bones. Before beginning the mobilization in palmar direction, joint slack is taken. Index fingers and thumbs are the major contact points which apply the force. Extension movement is applied through local grip with simultaneous wrist extension. Oscillation is finished while forearm turns back to primary position(12).</i_keyword>
      <i_keyword>Intervention group: The technique was done in 3 sets of 6 movements and lasted about 2/5 minutes. The Mulligan technique includes carpal lateral glide with non-weight bearing wrist flexion/extension. The subject is in sitting position with the elbow in 90˚ flexion, the forearm in mid pronation, the wrist in resting position and the hand in neutral position. The therapist is in front of the subject and fixes the distal end of the radius laterally with the first web space. The therapist’s other hand grasped the medial side of the subject’s wrist joint. Then through the first web space a lateral glide was applied to the proximal carps. While the therapist was maintaining the lateral glide, the subject was asked to flex and extend her wrist and apply the pressure at the end of movement in favor of wrist extension. If required, slight adjustments were made to the intensity and direction of the lateral glide.    Because the wrist joint was small, the mobilization was done slowly.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Grip strength. Timepoint: Pre and immediately post intervention. Method of measurement: A hand dynamometer – model SH 5002, SAEHAN.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome>Absolute error. Timepoint: Pre and immediately post intervention. Method of measurement: A hand dynamometer – model SH 5002, SAEHAN.</sec_outcome>
      <sec_outcome>Constant error. Timepoint: Pre and immediately post intervention. Method of measurement: A hand dynamometer – model SH 5002, SAEHAN.</sec_outcome>
      <sec_outcome>Variable error. Timepoint: Pre and immediately post intervention. Method of measurement: A hand dynamometer – model SH 5002, SAEHAN.</sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Shahid Beheshti University of Medical Sciences</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2017-07-11</approval_date>
        <contact_name>Ethics committee of Shahid Beheshti University of Medical Sciences, Tehran , Iran.</contact_name>
        <contact_address>1616913111, Damavand AVE, Imam Hossein SQ, Tehran, Iran. Tehran Tehran Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
