IRCT20180630040290N2 IRCT 2019-03-27 Tabriz University of Medical Sciences The Effect of Probiotic Supplementation in the form of Mouthwash with Scaling and Root planing on the Periodontal Indeces in Patients with Generalized Chronic Periodontitis Clinical trial The Effect of Probiotic Supplementation in the form of Mouthwash with Scaling and Root planing on the Periodontal Indeces in Patients with Generalized Chronic Periodontitis 2019-03-01 anticipated 36 Complete https://irct.ir/trial/37523 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Randomization description: Simple randomization. In this study, patients are assigned to one of two study groups using the random number table, Blinding description: Probiotic and placebo supplements are in the same packages (shape, size, and color that are almost the same). The supplements will be purchased from Milad Pharmed company and will be available to patients. 3 The effect of probiotic supplementation in the form of mouthwash with scaling and root planing on the periodontal indeces in patients with generalized chronic periodontitis. Intervention 1: Intervention group: The intervention group after SRP will use probiotic for 20 days by daily solution of two probiotic capsules in 250 cc water and then will gargle in the mouth for 30 to 60 seconds to increase its local effect on the gum tissue. Intervention 2: The control group after SRP will use placebo (drinking water that has been stablished in terms of chemical compounds). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There are no more information.