IRCT20180430039488N1 IRCT 2019-03-28 Tehran Heart Center Efficacy of steroid treatment on heart blocks secondary to heart valve surgery Evaluation of the efficacy of high dose corticosteroid regimen for treatment of postoperative high degree Atrioventricular block after valvular cardiac surgery ; A single blind randomized clinical trial 2019-03-25 anticipated 150 Complete https://irct.ir/trial/37399 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: patients in control group receive standard medical care including TPM and monitoring while the others in intervention group receive corticosteroid regimen in addition to standard treatment, Randomization description: permuted block randomization containing 4 subjects in each block eg : AABB. A refers to intervention group and B refers to controls, Blinding description: Collected data of the study will be entered in the SPSS and then analysed by an independent expert from THC research institute. 3 Advanced atrioventricular block following heart valve surgery. Intervention 1: Intervention group: Administration of intravenous dexamethasone with dose of 0.4 mg per kg (maximum dose of 35 mg per day) in divided schedule for 3 consecutive days. All patients including control group have the support of temporary pacemaker and standard conservative treatments. Intervention 2: Control group: This group will receive standard treatment protocol including close monitoring of rhythm with support of a Temporary pace maker. Yes - There is a plan to make this available What will be shared: Particular parts of the data will be released When: After release of the results To whom: Scientific institutions Conditions: Further analysis Where to obtain: Dr Saeed Ghodsi How to obtain: Formal or official request by an institution Comments: