IRCT20190114042353N1 IRCT 2019-03-16 Vice-Chancellor of Research Affairs, Guilan University of Medical Sciences clinical effectiveness of mouthwash of arctium lappa tincture on the treatment of oral mucositis induced by chemoradiotherapy in patients with head and neck cancer clinical effectiveness of mouthwash of arctium lappa tincture on the treatment of oral mucositis induced by chemoradiotherapy in patients with head and neck cancer 2019-02-20 anticipated 52 Complete https://irct.ir/trial/37035 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization using a random number table, Blinding description: after accepting participation In the study,a bottle containing a mixture of burdock mouthwash and a diphenhydramine mouthwash was given to the patient that the patient was not aware of its contents. 2-3 oral mucositis. Intervention 1: Intervention group:Mouthwash burdock Tincture + Diphenhydramine mouthwash:The patient should hold 30 drops of mouthwash with some water in his mouth every day, four times a day, and then throw it out.(Before using this mouthwash, they should also use diphenhydramine combination mouthwash).as they should, First, keep 30 drops of mouthwash for 30 seconds and then throw it away.After 30 minutes, use the second mouthwash in the manner described. Intervention 2: Control group: Diphenhydramine combination mouthwash:The patient takes 30 drops of diphenhydramine mouthwash four times a day for 30 seconds in his mouth then throw it away. No - There is not a plan to make this available Justification or reason for not sharing IPD is Care for the secrets of patients