IRCT20131228015968N6 IRCT 2019-05-10 Vice chancellor for research, Shahid Beheshti University of Medical sciences- School of Nutrition Effects of sumac powder capsule (Rhus coriaria L.) with restricted calorie diet on obesity and depression Effects of sumac powder capsule (Rhus coriaria L.) with restricted calorie diet on anthropometric indices, body composition, level of inflammatory biomarkers, oxidative stress, appetite hormones, glycemic indices, lipid profile and depression in obese or overweight women with depression 2019-01-06 anticipated 60 Complete https://irct.ir/trial/36888 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Individuals are classified into overweight and obese groups based on body mass index and are randomly assigned to one of the sumac group or placebo group. The random grouping of the two groups is done using Stratified Blocked Randomization. Separate randomization is done within each group. The size of the blocks is 4, with two allocations to the intervention group (A) and two allocations to the placebo group (B). With 6 different permutations, AABB, ABAB, BBAA, BABA, ABBA, BAAB will be created, Blinding description: This study is a double blind clinical trial (patients and researchers). In order to implement this study, at the start of the study, a set of cans contains sumac or placebo are coded by a third party (someone other than the researchers) as A and B. N/A Condition 1: Overweight and obesity. Condition 2: depression. Intervention 1: Intervention group: daily intake of 3 g sumac powder as 3 capsules of 1000 mg before each meals with weight reduction diet for 12 weeks. Intervention 2: Control group: daily intake of 3 g starch as 3 capsules of 1000 mg before each meals with weight reduction diet for 12 weeks. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information