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IRCT20190114042357N1 IRCT 2019-03-13 Birjand University of Medical Sciences Comparison of ECG parameters before and after iron replacement therapy in iron deficient adolescents. The effect of standard Iron replacement therapy on ECG parameters in 9-18 years old adolescents 2019-01-30 anticipated 100 Complete https://irct.ir/trial/36845 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Prevention. N/A Iron deficiency. Patients with ferritin below 15 mg/dl and their parents will be educated for treatment of iron deficiency and importance of continuing treatment.Then will be treated by iron replacement with trade name of ferrous sulfate made by Daroopakhsh company and bach number:769,including 50 milligram of elemental Iron, 3 to 5 milligram per kilogram(max dose 150 mg) for 3 months. finally they will be visited and history and physical exam will be done.Then 12 lead standard electrocardiogram and blood sample for CBC and Ferritin will be taken similar to before treatment. Ferritin must be above 15 or the patient will be excluded of research. Then electrocardiogram markers will be conferred with before treatment.. Yes - There is a plan to make this available What will be shared: Labolatory results ECG records When: 6 months after publication of results To whom: Academic researchers Conditions: Use in systematic reviews Where to obtain: Via e-mail address:shahriarivahiddr@bums.ac.ir How to obtain: Request by e-mail and sending of results about two months later Comments:
public Vahid Shahriari
Birjand University of medical sciences, Ghafari Blvd
Birjand Iran (Islamic Republic of) ۹۷۱۷۸۵۳۵۷۷ +98 56 3239 5000 shahriarivahiddr@bums.ac.ir Birjand University of Medical Sciences scientific Vahid Shahriari
Birjand University of medical sciences, Ghafari Blvd
Birjand Iran (Islamic Republic of) ۹۷۱۷۸۵۳۵۷۷ +98 56 3239 5000 shahriarivahiddr@bums.ac.ir Birjand University of Medical Sciences Iran (Islamic Republic of) Parental concest Patient cooperation for taking history, physical examination,ECG and blood sampling Absence of inflammatory disease during three weeks according to history and physical examination. Absence of chronic renal disease Absence of rheumatologic,collagen vascular or other chronic disease Absence of any cardiac disease including congenital or inflammatory. Absence of any drug consumption in three recent weeks because of any probable effect on ECG parameters 9 years 18 years Both Acute inflammatory disease Hypothyroidism Treatment - Drugs Patients with ferritin below 15 mg/dl and their parents will be educated for treatment of iron deficiency and importance of continuing treatment.Then will be treated by iron replacement with trade name of ferrous sulfate made by Daroopakhsh company and bach number:769,including 50 milligram of elemental Iron, 3 to 5 milligram per kilogram(max dose 150 mg) for 3 months. finally they will be visited and history and physical exam will be done.Then 12 lead standard electrocardiogram and blood sample for CBC and Ferritin will be taken similar to before treatment. Ferritin must be above 15 or the patient will be excluded of research. Then electrocardiogram markers will be conferred with before treatment. Serum ferritin level. Timepoint: QTc distance measurement. Method of measurement: Ferritin measurment by electrochemiluminescence method by Cobas Japan and Roche kit Germany. Serum ferritin level. Timepoint: QTc distance measurment. Method of measurement: Ferritin measurment by electrochemiluminescence method by Cobas Japan and Roshe kit Germany. Birjand University of Medical Sciences Approved 2018-06-20 Ethics committee of Birjand university of medical sciences Ghafari Blvd. Birjand South Khorasan Iran (Islamic Republic of)