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IRCT201103023565N3 IRCT 2011-03-29 Tabriz University of Medical Sciences Effect of dexamethasone on the goiterous size Effect of intrathyroidal dexamethasone injection on the goiterous size, clinical and biochemical course of goiterous Hashimoto's thyroiditis with subclinical hypothyroidism 2010-11-05 anticipated 40 Complete https://irct.ir/trial/3660 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Goiterous Hashimoto's thyroiditis with subclinical Hyothyroidism. Intervention 1: Dexamethasone injection protocol within three months with needle No 25 (0/25 mm) under ultrasound guidance. Intervention 2: Patients in control group followed their routine life activities without any therapeutic plan.
public Dr Akbar Aliasgharzadeha
Azadi Street, Golgasht Avenue, Tabriz
Tabriz Iran (Islamic Republic of) +98 914 402 4918 asgharzadeha@gmail.com Emam Reza hospital scientific Dr Akbar Aliasgharzadeha
Azadi Street, Golgasht Avenue, Tabriz
Tabriz Iran (Islamic Republic of) +98 914 402 4918 asgharzadeha@gmail.com Tabriz University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: goiterous Hashimoto's thyroiditis with subclinical hypothyroidism, TSH ≥ 10 mIU/L, AntiTPO + or AntiTG Exclusion criteria: Age between 15 and more than70, Use of corticosteroids therapy dose in the past six months for any reason, Use of antithyroid drugs at the baseline, Psychotic and psycho somatic diseases, Atrophic form of goiterous Hashimoto's thyroiditis, no consent to participate in the study 15 years 70 years Both E06.3 Treatment - Drugs Treatment - Drugs Dexamethasone injection protocol within three months with needle No 25 (0/25 mm) under ultrasound guidance Patients in control group followed their routine life activities without any therapeutic plan (TSH) Thyroid Stimulating Hormone. Timepoint: Baseline, the end of the third month and sixth month end. Method of measurement: Laboratory. Antibody Against Thyroid Peroxidase (Anti TPO). Timepoint: Baseline, the end of the third month and sixth month end. Method of measurement: Laboratory. Goiterous size. Timepoint: Baseline, the end of the third month and sixth month end. Method of measurement: Radiology. Tabriz University of Medical Sciences Approved 2011-02-14 Tabriz University of Medical Sciences Tabriz University of Medical Sciences, Golgasht Avenue, Tabriz Tabriz Iran (Islamic Republic of)