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IRCT20181229042166N1 IRCT 2019-04-06 Arak University of Medical Sciences Effect of centella asiatica on pain and wound healing of burns The effect of Oral Centella Asiatica on pain and wound healing of burns 2019-02-09 anticipated 76 Complete https://irct.ir/trial/36530 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Randomization description: Ranomized block design and selection of 6th and 8th blocks.Individual randomization unit.for randomise , first for random allocation ,Random sequence created with use of ''random allocation soft ware ''and then based on volume sample that is 76,76 envelopes with aluminium cover were provided and each of random Sequence were registered on a card and placed in the envelope orderly. for keeping random Sequence on orderthe outer surface of envelopes ,numbering is performed in the same way .the envelopes are Pasted and placed orderly inside the box and Based on the entry of participants to the study ,on of the envelopes are opened.then that participant 's allocated group is revealed, Blinding description: In order to eliminate the bias caused by the patient or physician's knowledge of the type of treatment received and its possible effect on the outcome of the study, the study is done Double blind . Due to the fact that the centella Asiatica and placebo capsules are placed in the same full capsule, it is natural that the patient and the person evaluating the received medication are unaware. 3 second Degree burn. Intervention 1: The intervention group will receive two capsules250 mg centella asiatica ; prepared by the Medicines Department of Karaj Jahad University; for two weeks. Intervention 2: Control group will received two 250 mg starch capsules; prepared by the Medicines Department of Karaj Jahad University; daily for two weeks. No - There is not a plan to make this available Justification or reason for not sharing IPD is No more information
public Robabeh Kazemi Dermanaki Farahani
No.1,Ettehad Alley.,Etteha Ave., Barekat Square.,Hmid Town Hamid Town
Arak Iran (Islamic Republic of) 3816986658 +98 86 3324 7899 r.kazemidermanaki@arakmu.ac.ir Arak University of Medical Sciences scientific Kobra Rahzani
Arak University of Medical Sciences, Sardasht Sq.
Arak Iran (Islamic Republic of) 3848176941 +98 86 3417 3524 k.rahzani@yahoo.com Arak University of Medical Sciences Iran (Islamic Republic of) second degree burn Burn percent 15-55% (according to Land Browder chart) volunteer of presence to study Hospitalized in burn section 15-55 age limits at the most after 48 hours of burning No fasting 18 years 55 years Both Unwillingness to participate in the study Pregnancy being affected to underlying diseases like diabetes ,cancer, infectious diseases, hypertension Drug Addiction Allergy psychosis disorder Lactation T30.2 Burn of second degree, body region unspecified Treatment - Other Placebo The intervention group will receive two capsules250 mg centella asiatica ; prepared by the Medicines Department of Karaj Jahad University; for two weeks. Control group will received two 250 mg starch capsules; prepared by the Medicines Department of Karaj Jahad University; daily for two weeks Pain. Timepoint: Daily. For two weeks after the intervention began. Method of measurement: VAS TOOL(Visual analogue scale). Wound healing. Timepoint: Before the intervention and one and two weeks after the intervention began. Method of measurement: Bates -Jensen wound Assessment Tool. Burn percentage. Timepoint: Before the intervention and two weeks after the intervention. Method of measurement: Landdbrooder chart. Arak University of Medical Sciences Approved 2018-10-21 Ethics Committee of Arak University of Medical Sciences Arak Medical Sciences University,Rah Ahan Ave.,Allamalhoda st., Arak Markazi Iran (Islamic Republic of)