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IRCT201412033451N2 IRCT 2014-12-23 Dental Material Center , School of Dentistry , Babol University of Medical Sciences Determining concentration of Azithromycin in GCF after single dose adminstration Concentration of Azithromycin in GCF Determining concentration of Azitromycin in GCF after single dose administration in healthy subjects (by HPLC method) 2014-12-26 anticipated 30 Complete https://irct.ir/trial/3559 interventional Randomization: N/A, Blinding: Double blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. N/A Condition 1: Determine Concentration of Azithromycin in gingival crevicular fluid. Condition 2: Concentration of Azithromycin in gingival crevicular fluid. A group of 30 individuals were selected and a single dose of 250 mg Azithromycin were prescribed..
public Dr Mahmood Khosravi Samani
Babol University of Medical Sciences , Ganj afrooz street
Babol Iran (Islamic Republic of) 47176 +98 11 3219 9592 m.khosravi@mubabol.ac.ir Babol University of Medical Sciences scientific Dr Aliakbar Moghadamnia
Department of Pharmacology , Faculty of Medicine , Babol University of Medical Sciences
Babol Iran (Islamic Republic of) 4717641367 +98 11 3219 9592 a.moghadamnia@mubabol.ac.ir Babol University of Medical Sciences Iran (Islamic Republic of) The eligible and healthy volunteers will be enrolled in this case study only after receiving adequate information regarding purpose of the subject research and providing their consent for participation. Inclusion criteria: are having a gingival index less than 1.5 ; have adequate oral and general health conditions The exclusion criteria : are taking any oral medication in the last two weeks ; having an allergic reaction to Azithromycin ; gingivitis ; periodontitis ; showing any signs of gingival recession. 18 years 35 years Both Z01.2 Z01 Dental examination Other special examinations and investigations of persons without complaint or reported diagnosis Treatment - Drugs A group of 30 individuals were selected and a single dose of 250 mg Azithromycin were prescribed. Concentration of Azithromycin in GCF. Timepoint: Ine the 0 . 6 . 12 36 . 84 . 156 hours azithromycin concentrations in GCF checked. Method of measurement: We used HPLC method for measuring Concentration of Azithromycin in GCF. Dental Material Center , School of Dentistry , Babol University of Medical Sciences Approved 2014-06-09 Babol University of Medical Sciences University of Medical Sciences-ganj afrooz avenu babol Iran (Islamic Republic of)