]>
IRCT20100412003690N9 IRCT 2018-12-08 Tabriz University of Medical Sciences Effects of systemic melatonin and non surgical periodontal therapy on serum ferritin inpatients with periodontitis disease Effects of systemic melatonin and non surgical periodontal therapy on serum ferritin inpatients with periodontitis disease 2018-11-26 anticipated 42 Complete https://irct.ir/trial/35379 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: Referring patients with periodontitis to Tabriz Faculty Of Dentistry are numbered, after observing the entry and exit requirements of the study. Then, using a random number table, we select 42 numbers from this table and enter the subject, Blinding description: In this study, the participating patients and physician will be informed of the type of treatment intervention (1-Chlorhexidine mouthwash 2- Melatonin oral administration), however, the evaluator of the results will not be aware of the intervention method, so the study will be single-blind. N/A Periodontitis. Intervention 1: Intervention group:The Vi-One chlorohexidine 2%mouthwash will be used for one minute to wash teeth in the morning and at night, and oral melatonin tablets will be taken for a period of 30 days once a day before bedtime. Intervention 2: Control group: Chlorhexidine mouthwash for 30 days. Yes - There is a plan to make this available What will be shared: The data obtained from the participants can be presented in the form of a table. The protocol for the study, which is routine methods, has no problems with its publication. Statistical analysis can also be provided. In this study, an informed consent form will be used that can be published without mentioning the person's name and personal details. A clinical study report can be made after the necessary analyzes. When: Start the access period 9 months after publishing the results To whom: For researchers in Dental school of Tabriz University Conditions: For scholars working in other academic and academic institutions, if approved by the project implementer Where to obtain: Dr. Masoomeh Faramarzi, email or phone Dental school of Tabriz University, Periodontics department, 9144113420 0098 ، faramarzim@tbzmed.ac.ir How to obtain: After receiving the request will be answered within a week. Comments:
public Masoomeh Faramarzie
Golgasht Ave, Tabriz
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 3335 5965 faramarzim@tbzmed.ac.ir Tabriz University of Medical Sciences scientific Masoomeh Faramarzie
Golgasht Ave, Tabriz
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 3335 5965 faramarzim@tbzmed.ac.ir Tabriz University of Medical Sciences Iran (Islamic Republic of) 1. Lake of loss the joints in interdental areas larger than 4 mm. 2.Absent depth of the envelope larger than 4 mm in the interdental areas. 3. The bleeding tendency is less or equal to 10% in total. 4. Age older than twenty years 20 years no limit Both 1. People with systemic disorders, such as epilepsy, schizophrenia, chronic infections, neoplastic disease, or any disease that affects the immune system. 2.Invader Periodontium 3. Smokers and Alcoholics 4. Pregnancy or breastfeeding 5. Patients taking medications that can affect the level of melatonin 6. Those who have had periodontal treatment in the last 6 months. 7.People working in night shifts. 8.Under-20years. 9.People with mental disabilities K05.3 Chronic periodontitis Treatment - Drugs Treatment - Drugs Intervention group:The Vi-One chlorohexidine 2%mouthwash will be used for one minute to wash teeth in the morning and at night, and oral melatonin tablets will be taken for a period of 30 days once a day before bedtime. Control group: Chlorhexidine mouthwash for 30 days Serum ferritin level. Timepoint: Before the start, One and three months later. Method of measurement: Blood sampling. Tabriz University of Medical Sciences Approved 2018-11-19 Ethics committee of Tabriz University of Medical Sciences International Relations Office, No 2 Central Building, Tabriz University of Medical Sciences, University Street, Tabriz Tabriz East Azarbaijan Iran (Islamic Republic of)