IRCT138812083436N1 IRCT 2012-08-07 Shahid Beheshti University of Medical Sciences Anesthesia for the Child with Mild Upper Respiratory Tract Infection: Comparison of intravenous vs. topical lidocaine Anesthesia for the Child with Mild Upper Respiratory Tract Infection: Comparison of intravenous vs. topical lidocaine 2011-12-12 anticipated 130 Complete https://irct.ir/trial/3510 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention. 2-3 Acute nasopharyngitis. Intervention 1: intravenous lidocaine (1.5 mg/kg). Intervention 2: intravenous normal saline. Intervention 3: Topical lidocaine (2% lidocaine) on laryngeal mask airway. Intervention 4: Topical lubrication gel on laryngeal mask airway.

public Babak Gharaei

Labbafinejad Hospital, 9th Boostan ,Pasdaran

Tehran Iran (Islamic Republic of) +98 21 2254 9029 babakgharaei@gmail.combabakgharaei@yahoo.com Shahid Beheshti University of Medical Sciences scientific Babak Gharaei

Labbafinejad Hospital, 9th Boostan, Pasdaran

Tehran Iran (Islamic Republic of) +98 21 2254 9029 babakgharaei@gmail.combabakgharaei@yahoo.com Shahid Beheshti University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: All pediatric patients between 1-6 y-old whose parents mentioned mild URI symptoms (nasal discharge or congestion, cough, sneeze) started within last two weeks No evidence of bacterial infection (axillary temperature more than 38, ill appearance evaluated by anesthesiologist in charge, purulent discharge or sputum) No evidence of lower respiratory infection (crackle or wheeze) No evidence of medical condition (respiratory, cardiac or neurologic) Patients candidate for anesthesia to receive full ophthalmologic examination. These procedures were necessary to perform and further delay would have deleterious consequences. Exclusion criteria: Those with a probable difficult airway Hypersensitivity to drugs Patients who received hydrocortisone, dexamethasone or extra atropine and vasopressor Those who required muscle relaxant due to unpredicted surgery plan change or procedures lasting more than an hour 1 year 6 years Both J00 Coryza (acute)Nasal catarrh, acute Nasopharyngitis Prevention Placebo Prevention Placebo intravenous lidocaine (1.5 mg/kg) intravenous normal saline Topical lidocaine (2% lidocaine) on laryngeal mask airway Topical lubrication gel on laryngeal mask airway Cough. Timepoint: Induction, maintenance, emergence, recovery. Method of measurement: observation and questionnaire. Desaturation (SPO2 less than 90% for more than one minute). Timepoint: induction, maintenace, emergence and recovery (continuous). Method of measurement: pulsoximetry. Apnea (no airflow for more than 10 seconds). Timepoint: induction, maintenace, emergence and recovery. Method of measurement: Observation. Laryngospasm (inspiratory stridor). Timepoint: induction, maintenance, emergence and recovery (every 5 minutes). Method of measurement: observation and questionnaire. Bronchospasm (inspiratory or expiratory wheeze). Timepoint: induction, maintenance, emergence and recovery (every 5 minutes). Method of measurement: observation and questionnaire. Vomiting. Timepoint: induction, maintenance, emergence and recovery (every 5 minutes). Method of measurement: observation and questionnaire. Cardiac event (any medication for cardiac support). Timepoint: induction, maintenance, emergence and recovery. Method of measurement: questionnaire. Shahid Beheshti University of Medical Sciences Approved 2011-12-11 Shahid Beheshti University of Medical Sciences/Ethics Committee Chamran- Evin- side to Taleghani Hospital Tehran Iran (Islamic Republic of)