<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT138903163417N2</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2012-08-27</date_registration>
      <primary_sponsor>Research Assistance Shahid Beheshti Nursing and Midwifery University</primary_sponsor>
      <public_title>Reflexology impact on reducing vomiting in patients undergoing chemotherapy</public_title>
      <acronym></acronym>
      <scientific_title>Reflexology impact on reducing vomiting in patients undergoing chemotherapy Oncology - Hematology Hospital Ali Ibn Abi Talib (AS) University in 1388</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2009-09-23</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>35</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/3495</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Other.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Vomiting caused by chemotherapy.</hc_freetext>
      <i_freetext>Intervention 1: Control group in this study received anti-vomiting and Granisetron efficacious half-life 12-9 hours, which coincided with the start of chemotherapy were administered 3 mg and the doctor ordered.Granisetron injections per patient since the beginning of chemotherapy and 24 hours (if admitted in part, by the researcher as a personAnd in case of discharge, a telephone by the researcher) was studied.So the second part of the questionnaire survey vomiting In four separate times by the end of 24 hours were completed.(4 hours, 4 hours, second, third, 4 hours, 12 second). Intervention 2: Samples in the next month (with a distance of 15 to 20 days before the visit) were in the intervention group. Before, the patient explained that in addition to all therapeutic measures that will be done as before, the pressure point for his feet will be and also to ensure patients were in case of vomiting, the drug was injected again. Simultaneously with the start of chemotherapy, drug Granisetron was used but in the case of severe and distressing vomiting or vomiting for 24 hours was more than 5 times; in case of hospitalized patients and vomiting in the drug Granisetron was used and the patient was in attendance and was controlled by telephone from IV metoclopramide was used). Intervention for this group was to put pressure on the solar system. Reflection points for this area, both feet on the floor, just below the center of the foot, connecting the midpoint of the second and third metatarsal bones and in case the patient flat on his back lying down or sitting by fines thumb, press firmly on the area to the pain by the patient at the same point be expressed, were applied in this work from the other fingers and hands other support was used. The first operation was performed on the right foot then left foot (10 minutes for each leg). After the massage, the patient started chemotherapy and reflexology performed by researchers at four separate time from the questionnaires were completed by the second part (4 hours, 4 hours, second, third, 4 hours, 12 second).</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan></results_IPD_plan>
      <results_IPD_description></results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Nazanin Yousefian Miandoab</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Zahedan - Blvarbhdasht - Circle of Mashahir- University School of Nursing</address>
        <city>Zahedan</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip></zip>
        <telephone>+98 54 1322 6386</telephone>
        <email>n.yoosefian@yahoo.com</email>
        <affiliation>University School of Nursing</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Ezzati Jaleh</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Tehran - Shariati St - end Mirdamad Alley - Gift - Graduate School of Nursing and Midwifery martyr Beheshti</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip></zip>
        <telephone>+98 22229648</telephone>
        <email>j_ezati@sbmu.ac.ir</email>
        <affiliation>Shahid Beheshti Nursing and Midwifery University</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Inclusion criteria: &#13;
.1 - be alert. (Awareness of time and place and person) 2 - have over 18 years of age 3 - spent at least one course of chemotherapy and chemotherapy with drugs or treatment of moderate to severe can cause vomiting.4 - Side effects of acute vomiting that has occurred. 5 - other treatments such as radiation therapy during the study, it is not in the program. 6 - a-day drug regimen should be treated.&#13;
Exclusion criteria &#13;
1- were examples of women during pregnancy and menstruation. 2 - Examples disease such as fever, leukemia, epilepsy, cellulitis and infection, deep vein thrombosis and psychosis and gastric cancer, thrombosis and was paralyzed. (Banned because of the reflections) 3 - Examples of problems in the leg were impaired and if the intervention was painful for them.</inclusion_criteria>
      <agemin>no limit</agemin>
      <agemax>75 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria></exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>R11</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Nausea and vomiting</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Treatment - Drugs</i_code>
      <i_code>Prevention</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Control group in this study received anti-vomiting and Granisetron efficacious half-life 12-9 hours, which coincided with the start of chemotherapy were administered 3 mg and the doctor ordered.Granisetron injections per patient since the beginning of chemotherapy and 24 hours (if admitted in part, by the researcher as a personAnd in case of discharge, a telephone by the researcher) was studied.So the second part of the questionnaire survey vomiting In four separate times by the end of 24 hours were completed.(4 hours, 4 hours, second, third, 4 hours, 12 second).</i_keyword>
      <i_keyword>Samples in the next month (with a distance of 15 to 20 days before the visit) were in the intervention group. Before, the patient explained that in addition to all therapeutic measures that will be done as before, the pressure point for his feet will be and also to ensure patients were in case of vomiting, the drug was injected again. Simultaneously with the start of chemotherapy, drug Granisetron was used but in the case of severe and distressing vomiting or vomiting for 24 hours was more than 5 times; in case of hospitalized patients and vomiting in the drug Granisetron was used and the patient was in attendance and was controlled by telephone from IV metoclopramide was used). Intervention for this group was to put pressure on the solar system. Reflection points for this area, both feet on the floor, just below the center of the foot, connecting the midpoint of the second and third metatarsal bones and in case the patient flat on his back lying down or sitting by fines thumb, press firmly on the area to the pain by the patient at the same point be expressed, were applied in this work from the other fingers and hands other support was used. The first operation was performed on the right foot then left foot (10 minutes for each leg). After the massage, the patient started chemotherapy and reflexology performed by researchers at four separate time from the questionnaires were completed by the second part (4 hours, 4 hours, second, third, 4 hours, 12 second).</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Reduce the number of acute vomiting in patients undergoing chemotherapy treatment method using Reflection. Timepoint: (first 4 hours -second 4 hours - third 4 hours) first 12 hours and  second 12 hours after the intervention. Method of measurement: Questionnaire vomiting (a combination of questionnaires and the Moro National Cancer Institute Toxicity Criteria version 2 manual America).</prim_outcome>
      <prim_outcome>Reduce the severity of acute vomiting in patients undergoing chemotherapy treatment method using Reflection. Timepoint: (first 4 hours -second 4 hours - third 4 hours) first 12 hours and  second 12 hours after the interventionr the second. Method of measurement: Questionnaire vomiting (a combination of questionnaires and the Moro National Cancer Institute Toxicity Criteria version 2 manual America).</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Research Assistance Shahid Beheshti Nursing and Midwifery University</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2009-09-20</approval_date>
        <contact_name>International Branch martyr Beheshti University of Medical Sciences and Health Services</contact_name>
        <contact_address>Street, Vali-Asr Avenue - martyr Abbaspour (Tavanir) - St. Paul Hammett - No. 19 Tehran  Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2010-01-05</approval_date>
        <contact_name>Zahedan University of Medical Sciences</contact_name>
        <contact_address>Persian Gulf Boulevard - Medical Sciences Campus - Research Zahedan  Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
